Chlorine in PDB 1zj3: Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide

The structure of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide, PDB code: 1zj3 was solved by J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.69
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	52.600, 150.800, 79.700, 90.00, 90.00, 90.00
R / Rfree (%)	20.4 / 23

The structure of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide also contains other interesting chemical elements:

Mercury

(Hg)

6 atoms

The binding sites of Chlorine atom in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide (pdb code 1zj3). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide, PDB code: 1zj3:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl406 b:36.8 occ:0.60 HG A:HG402 2.5 27.5 0.5 HG A:HG405 3.1 29.4 0.2 CB A:CYS209 3.5 21.0 1.0 SG A:CYS209 3.5 28.9 1.0 CZ A:PHE270 3.6 20.2 1.0 CL A:CL407 3.8 27.4 0.5 OG1 A:THR119 4.3 25.3 1.0 CE1 A:PHE270 4.3 19.4 1.0 CE2 A:PHE270 4.5 20.9 1.0 CG2 A:THR281 4.5 25.8 1.0 CE1 A:PHE121 4.7 37.1 1.0 CA A:CYS209 4.8 19.2 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Galactosyltransferase (Gtb) Complexed with H Type II Trisaccharide within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl407 b:27.4 occ:0.50 O A:HOH624 2.7 36.2 1.0 HG A:HG405 2.8 29.4 0.2 CB A:CYS209 3.5 21.0 1.0 C A:CYS209 3.7 18.8 1.0 N A:VAL210 3.8 18.8 1.0 CL A:CL406 3.8 36.8 0.6 O A:VAL210 3.9 19.5 1.0 O A:CYS209 4.0 17.9 1.0 CE2 A:PHE270 4.0 20.9 1.0 CA A:CYS209 4.1 19.2 1.0 C A:VAL210 4.1 20.1 1.0 O A:HOH547 4.1 29.8 1.0 CA A:VAL210 4.3 18.2 1.0 CZ A:PHE270 4.4 20.2 1.0 O A:GLY267 4.6 22.5 1.0 OD1 A:ASP211 4.6 29.5 1.0 CD2 A:PHE270 4.9 19.7 1.0 N A:ASP211 4.9 20.7 1.0

J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans. Differential Recognition of the Type I and II H Antigen Acceptors By the Human Abo(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem. V. 281 3625 2006.
ISSN: ISSN 0021-9258
PubMed: 16326711
DOI: 10.1074/JBC.M507620200