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Atomistry » Chlorine » PDB 1zoo-231l » 1zrb » |
Chlorine in PDB 1zrb: Thrombin in Complex with An Azafluorenyl Inhibitor 23BEnzymatic activity of Thrombin in Complex with An Azafluorenyl Inhibitor 23B
All present enzymatic activity of Thrombin in Complex with An Azafluorenyl Inhibitor 23B:
3.4.21.5; Protein crystallography data
The structure of Thrombin in Complex with An Azafluorenyl Inhibitor 23B, PDB code: 1zrb
was solved by
K.J.Stauffer,
P.D.Williams,
H.G.Selnick,
P.G.Nantermet,
C.L.Newton,
C.F.Homnick,
M.M.Zrada,
S.D.Lewis,
B.J.Lucas,
J.A.Krueger,
B.L.Pietrak,
E.A.Lyle,
R.Singh,
C.Miller-Stein,
R.B.White,
B.Wong,
A.A.Wallace,
G.R.Sitko,
J.J.Cook,
M.A.Holahan,
M.Stranieri-Michener,
Y.M.Leonard,
J.J.Lynch Jr.,
D.R.Mcmasters,
Y.Yan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Thrombin in Complex with An Azafluorenyl Inhibitor 23B
(pdb code 1zrb). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Thrombin in Complex with An Azafluorenyl Inhibitor 23B, PDB code: 1zrb: Chlorine binding site 1 out of 1 in 1zrbGo back to Chlorine Binding Sites List in 1zrb
Chlorine binding site 1 out
of 1 in the Thrombin in Complex with An Azafluorenyl Inhibitor 23B
Mono view Stereo pair view
Reference:
K.J.Stauffer,
P.D.Williams,
H.G.Selnick,
P.G.Nantermet,
C.L.Newton,
C.F.Homnick,
M.M.Zrada,
S.D.Lewis,
B.J.Lucas,
J.A.Krueger,
B.L.Pietrak,
E.A.Lyle,
R.Singh,
C.Miller-Stein,
R.B.White,
B.Wong,
A.A.Wallace,
G.R.Sitko,
J.J.Cook,
M.A.Holahan,
M.Stranieri-Michener,
Y.M.Leonard,
J.J.Lynch Jr.,
D.R.Mcmasters,
Y.Yan.
9-Hydroxyazafluorenes and Their Use in Thrombin Inhibitors J.Med.Chem. V. 48 2282 2005.
Page generated: Sat Dec 12 08:57:23 2020
ISSN: ISSN 0022-2623 PubMed: 15801822 DOI: 10.1021/JM049423S |
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