Chlorine in PDB 246l: The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect

All present enzymatic activity of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect:
3.2.1.17;

The structure of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect, PDB code: 246l was solved by J.Xu, W.A.Baase, E.Baldwin, B.W.Matthews, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 1.80
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	60.820, 60.820, 96.980, 90.00, 90.00, 120.00
R / Rfree (%)	16 / n/a

The binding sites of Chlorine atom in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect (pdb code 246l). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect, PDB code: 246l:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl173 b:35.6 occ:1.00 O A:HOH209 3.0 26.5 1.0 N A:ARG145 3.3 11.6 1.0 N A:ASN144 3.4 7.6 1.0 C A:THR142 3.5 22.2 1.0 CA A:THR142 3.5 12.2 1.0 CB A:THR142 3.7 15.0 1.0 CB A:ASN144 3.7 10.9 1.0 O A:THR142 3.8 12.2 1.0 N A:PRO143 3.8 15.9 1.0 CA A:ASN144 3.9 17.4 1.0 CB A:ARG145 4.0 11.2 1.0 C A:ASN144 4.1 17.4 1.0 CD A:PRO143 4.2 12.5 1.0 C A:PRO143 4.2 18.0 1.0 CA A:ARG145 4.3 9.2 1.0 CG2 A:THR142 4.4 11.3 1.0 CG A:ASN144 4.5 36.1 1.0 O A:HOH230 4.5 35.6 1.0 CA A:PRO143 4.6 11.0 1.0 ND2 A:ASN144 4.6 26.9 1.0 OG1 A:THR142 4.9 17.9 1.0 N A:THR142 4.9 13.9 1.0

Chlorine binding site 2 out of 2 in the The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl178 b:30.6 occ:0.50 O A:HOH215 3.0 20.3 1.0 O A:HOH200 3.0 28.1 1.0 O A:HOH182 3.1 23.2 1.0 O A:HOH246 3.7 53.2 1.0 CE1 A:HIS31 3.8 17.5 1.0 NE2 A:HIS31 4.0 14.5 1.0 CB A:ALA49 4.0 14.8 1.0 NE2 A:GLN69 4.4 14.4 1.0 O A:HOH282 4.5 37.4 1.0 O A:HOH202 4.5 46.9 1.0 CA A:ALA49 4.6 20.8 1.0 CD2 A:LEU66 4.7 16.6 1.0

J.Xu, W.A.Baase, E.Baldwin, B.W.Matthews. The Response of T4 Lysozyme to Large-to-Small Substitutions Within the Core and Its Relation to the Hydrophobic Effect. Protein Sci. V. 7 158 1998.
ISSN: ISSN 0961-8368
PubMed: 9514271