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Chlorine in PDB 2a8b: Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R

Enzymatic activity of Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R

All present enzymatic activity of Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R:
3.1.3.48;

Protein crystallography data

The structure of Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R, PDB code: 2a8b was solved by E.Ugochukwu, J.Eswaran, A.Barr, E.Longman, C.Arrowsmith, A.Edwards, M.Sundstrom, F.Von Delft, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 62.30 / 2.30
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 63.193, 74.098, 62.328, 90.00, 90.00, 90.00
R / Rfree (%) 19.2 / 25.6

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R (pdb code 2a8b). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R, PDB code: 2a8b:

Chlorine binding site 1 out of 1 in 2a8b

Go back to Chlorine Binding Sites List in 2a8b
Chlorine binding site 1 out of 1 in the Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Catalytic Domain of Human Tyrosine Phosphatase Receptor, Type R within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl200

b:38.5
occ:1.00
N A:ILE511 3.3 31.4 1.0
CA A:GLY510 3.7 30.7 1.0
C A:GLY510 3.9 31.2 1.0
CB A:ILE511 4.2 31.6 1.0
CA A:ILE511 4.3 31.5 1.0
O A:ARG509 4.5 31.2 1.0
CD1 A:ILE511 4.5 33.5 1.0
CG1 A:ILE511 4.6 31.9 1.0
N A:GLY510 4.6 30.8 1.0
O A:ILE511 4.7 31.8 1.0
NH1 A:ARG509 4.9 34.1 1.0
C A:ARG509 4.9 31.0 1.0

Reference:

J.Eswaran, J.P.Von Kries, B.Marsden, E.Longman, J.E.Debreczeni, E.Ugochukwu, A.Turnbull, W.H.Lee, S.Knapp, A.J.Barr. Crystal Structures and Inhibitor Identification For PTPN5, Ptprr and PTPN7: A Family of Human Mapk-Specific Protein Tyrosine Phosphatases. Biochem.J. V. 395 483 2006.
ISSN: ISSN 0264-6021
PubMed: 16441242
DOI: 10.1042/BJ20051931
Page generated: Sat Dec 12 08:58:24 2020

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