Chlorine in PDB 2a8w: Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with Beta-Methyllactoside

The structure of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with Beta-Methyllactoside, PDB code: 2a8w was solved by J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.59
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	52.620, 150.090, 79.550, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 23.2

The structure of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with Beta-Methyllactoside also contains other interesting chemical elements:

Mercury	(Hg)	5 atoms
Manganese	(Mn)	1 atom

The binding sites of Chlorine atom in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with Beta-Methyllactoside (pdb code 2a8w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with Beta-Methyllactoside, PDB code: 2a8w:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with Beta-Methyllactoside


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human N-Acetylgalactosaminyltransferase (Gta) Complexed with Beta-Methyllactoside within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl406 b:31.3 occ:1.00 O A:HOH722 2.7 41.5 1.0 HG A:HG402 2.7 43.9 0.3 O A:HOH552 2.8 31.1 1.0 N A:VAL210 3.5 17.5 1.0 O A:VAL210 3.5 19.4 1.0 C A:CYS209 3.6 16.7 1.0 CB A:CYS209 3.6 20.6 1.0 C A:VAL210 3.9 18.9 1.0 O A:CYS209 3.9 17.1 1.0 CA A:CYS209 4.0 18.3 1.0 CA A:VAL210 4.0 16.8 1.0 O A:HOH543 4.0 28.3 1.0 CE2 A:PHE270 4.5 21.3 1.0 O A:THR119 4.7 21.3 1.0 N A:ASP211 4.7 20.7 1.0 O A:GLY267 4.8 22.6 1.0 CD1 A:PHE121 4.8 35.0 1.0 CZ A:PHE270 4.9 21.4 1.0 OG1 A:THR119 4.9 24.8 1.0 OD2 A:ASP211 4.9 26.6 1.0

J.A.Letts, N.L.Rose, Y.R.Fang, C.H.Barry, S.N.Borisova, N.O.Seto, M.M.Palcic, S.V.Evans. Differential Recognition of the Type I and II H Antigen Acceptors By the Human Abo(H) Blood Group A and B Glycosyltransferases. J.Biol.Chem. V. 281 3625 2006.
ISSN: ISSN 0021-9258
PubMed: 16326711
DOI: 10.1074/JBC.M507620200