Chlorine in PDB 2b71: Plasmodium Yoelii Cyclophilin-Like Protein

The structure of Plasmodium Yoelii Cyclophilin-Like Protein, PDB code: 2b71 was solved by A.Dong, P.Finerty, G.Wasney, M.Vedadi, J.Lew, Y.Zhao, I.Kozieradzki, M.Melone, Z.Alam, A.M.Edwards, C.H.Arrowsmith, J.Weigelt, M.Sundstrom, A.Bochkarev, R.Hui, T.Hills, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.80 / 2.50
Space group	P 41 3 2
Cell size a, b, c (Å), α, β, γ (°)	132.399, 132.399, 132.399, 90.00, 90.00, 90.00
R / Rfree (%)	19 / 24.2

The binding sites of Chlorine atom in the Plasmodium Yoelii Cyclophilin-Like Protein (pdb code 2b71). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Plasmodium Yoelii Cyclophilin-Like Protein, PDB code: 2b71:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Plasmodium Yoelii Cyclophilin-Like Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Plasmodium Yoelii Cyclophilin-Like Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1000 b:28.6 occ:1.00 N A:TYR57 3.2 24.8 1.0 N A:TRP56 3.4 24.7 1.0 CB A:HIS35 3.7 26.3 1.0 CB A:TYR57 4.0 24.3 1.0 CB A:TRP56 4.0 23.1 1.0 C A:TYR55 4.0 24.7 1.0 CA A:TRP56 4.0 24.4 1.0 C A:TRP56 4.1 24.7 1.0 O A:LEU54 4.1 24.8 1.0 CA A:TYR57 4.1 24.9 1.0 CA A:TYR55 4.1 24.2 1.0 CG A:HIS35 4.3 29.9 1.0 CA A:HIS35 4.5 28.2 1.0 ND1 A:HIS35 4.6 34.0 1.0 N A:HIS35 4.6 27.9 1.0 O A:HOH1019 4.7 24.1 1.0 O A:TYR55 4.8 23.9 1.0 CG A:TRP56 4.9 23.5 1.0 CD1 A:TRP56 4.9 24.2 1.0 C A:LEU54 5.0 25.5 1.0

Chlorine binding site 2 out of 5 in the Plasmodium Yoelii Cyclophilin-Like Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Plasmodium Yoelii Cyclophilin-Like Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:39.6 occ:1.00 CD A:PRO145 3.4 29.0 1.0 N A:ALA122 3.4 27.2 1.0 CA A:GLY121 3.8 29.6 1.0 CA A:ALA144 3.9 27.0 1.0 CB A:ALA122 3.9 25.2 1.0 C A:GLY121 4.0 28.9 1.0 N A:PRO145 4.1 28.5 1.0 CA A:ALA122 4.2 27.4 1.0 C A:ALA144 4.3 27.7 1.0 CG A:PRO145 4.5 26.8 1.0 N A:ALA144 4.7 26.4 1.0 O A:LEU143 4.7 28.1 1.0 CB A:ALA144 4.8 25.2 1.0 C A:LEU143 5.0 25.9 1.0

Chlorine binding site 3 out of 5 in the Plasmodium Yoelii Cyclophilin-Like Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Plasmodium Yoelii Cyclophilin-Like Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1002 b:39.5 occ:1.00 N A:ASN86 2.9 24.8 1.0 O A:HOH1053 3.2 30.2 1.0 CA A:PRO85 3.4 25.1 1.0 C A:PRO85 3.6 24.8 1.0 CD1 A:LEU143 3.7 17.5 1.0 CB A:PRO85 3.8 23.7 1.0 CB A:LEU143 4.0 23.7 1.0 CA A:ASN86 4.0 27.6 1.0 CB A:ALA170 4.0 23.9 1.0 ND2 A:ASN86 4.1 36.2 1.0 CG A:LEU143 4.3 22.7 1.0 CG A:ASN86 4.5 34.0 1.0 O A:HOH1099 4.5 34.7 1.0 O A:HOH1074 4.6 38.2 1.0 CD2 A:LEU143 4.6 19.0 1.0 O A:LEU143 4.7 28.1 1.0 N A:PRO85 4.8 25.5 1.0 O A:PRO85 4.8 23.7 1.0 CB A:ASN86 4.9 28.4 1.0 CG A:PRO85 4.9 25.1 1.0

Chlorine binding site 4 out of 5 in the Plasmodium Yoelii Cyclophilin-Like Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Plasmodium Yoelii Cyclophilin-Like Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1003 b:67.2 occ:1.00 NH2 A:ARG82 3.0 36.2 1.0 O A:HOH1023 4.0 27.9 1.0 CZ A:ARG82 4.3 34.7 1.0 NE A:ARG82 4.9 33.5 1.0

Chlorine binding site 5 out of 5 in the Plasmodium Yoelii Cyclophilin-Like Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Plasmodium Yoelii Cyclophilin-Like Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1004 b:54.1 occ:1.00 O A:HOH1097 3.2 38.3 1.0 NE2 A:GLN90 3.3 41.2 1.0 OG A:SER128 3.5 40.8 1.0 NH1 A:ARG82 3.5 29.6 1.0 O A:HOH1062 3.6 26.3 1.0 O A:HOH1079 3.7 41.8 1.0 OE1 A:GLN90 3.9 32.9 1.0 CD A:GLN90 4.0 34.9 1.0 O A:ASN129 4.4 37.1 1.0 CZ A:ARG82 4.6 34.7 1.0 CE1 A:PHE140 4.6 40.3 1.0 CB A:SER128 4.9 33.7 1.0 NH2 A:ARG82 4.9 36.2 1.0 CZ A:PHE140 5.0 39.4 1.0

M.Vedadi, J.Lew, J.Artz, M.Amani, Y.Zhao, A.Dong, G.A.Wasney, M.Gao, T.Hills, S.Brokx, W.Qiu, S.Sharma, A.Diassiti, Z.Alam, M.Melone, A.Mulichak, A.Wernimont, J.Bray, P.Loppnau, O.Plotnikova, K.Newberry, E.Sundararajan, S.Houston, J.Walker, W.Tempel, A.Bochkarev, I.Kozieradzki, A.Edwards, C.Arrowsmith, D.Roos, K.Kain, R.Hui. Genome-Scale Protein Expression and Structural Biology of Plasmodium Falciparum and Related Apicomplexan Organisms. Mol.Biochem.Parasitol. V. 151 100 2007.
ISSN: ISSN 0166-6851
PubMed: 17125854
DOI: 10.1016/J.MOLBIOPARA.2006.10.011