Chlorine in PDB 2bwn: 5-Aminolevulinate Synthase From Rhodobacter Capsulatus

All present enzymatic activity of 5-Aminolevulinate Synthase From Rhodobacter Capsulatus:
2.3.1.37;

The structure of 5-Aminolevulinate Synthase From Rhodobacter Capsulatus, PDB code: 2bwn was solved by I.Astner, J.O.Schulze, J.J.Van Den Heuvel, D.Jahn, W.-D.Schubert, D.W.Heinz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	129.10 / 2.1
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	67.875, 92.872, 250.131, 90.00, 90.00, 90.00
R / Rfree (%)	16.1 / 21.7

The binding sites of Chlorine atom in the 5-Aminolevulinate Synthase From Rhodobacter Capsulatus (pdb code 2bwn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the 5-Aminolevulinate Synthase From Rhodobacter Capsulatus, PDB code: 2bwn:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the 5-Aminolevulinate Synthase From Rhodobacter Capsulatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of 5-Aminolevulinate Synthase From Rhodobacter Capsulatus within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1399 b:65.0 occ:1.00 NZ E:LYS150 3.4 33.4 0.5 CE E:LYS150 3.4 35.3 0.5 NH1 A:ARG157 3.6 18.3 1.0 NZ E:LYS156 3.7 17.7 0.5 O A:HOH2089 3.8 33.3 1.0 NH2 A:ARG157 3.9 20.5 1.0 CB A:PRO155 4.0 24.1 1.0 CE E:LYS156 4.1 23.8 0.5 CZ A:ARG157 4.3 16.4 1.0 CA A:PRO155 4.4 22.7 1.0 CG A:PRO155 4.8 25.0 1.0 CE E:LYS156 4.9 21.4 0.5 CD E:LYS150 4.9 34.3 0.5

Chlorine binding site 2 out of 2 in the 5-Aminolevulinate Synthase From Rhodobacter Capsulatus


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of 5-Aminolevulinate Synthase From Rhodobacter Capsulatus within 5.0Å range: probe atom residue distance (Å) B Occ E:Cl1402 b:69.0 occ:1.00 NH1 E:ARG157 3.7 22.8 1.0 NH2 E:ARG157 3.9 21.5 1.0 NZ A:LYS156 3.9 21.4 0.3 CB E:PRO155 4.2 24.1 1.0 CE A:LYS156 4.2 20.2 0.3 CZ E:ARG157 4.3 23.2 1.0 CA E:PRO155 4.7 22.8 1.0 CG E:PRO155 4.8 23.7 1.0 CE A:LYS156 4.9 29.3 0.7

I.Astner, J.O.Schulze, J.J.Van Den Heuvel, D.Jahn, W.-D.Schubert, D.W.Heinz. Crystal Structure of 5-Aminolevulinate Synthase, the First Enzyme of Heme Biosynthesis, and Its Link to Xlsa in Humans. Embo J. V. 24 3166 2005.
ISSN: ISSN 0261-4189
PubMed: 16121195
DOI: 10.1038/SJ.EMBOJ.7600792