Chlorine in PDB 2cx9: Crystal Structure of Acyl-Coa Dehydrogenase

All present enzymatic activity of Crystal Structure of Acyl-Coa Dehydrogenase:
1.3.99.3;

The structure of Crystal Structure of Acyl-Coa Dehydrogenase, PDB code: 2cx9 was solved by K.Murayama, T.Kinebuchi, M.Shirouzu, S.Yokoyama, Riken Structuralgenomics/Proteomics Initiative (Rsgi), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.55 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	75.685, 88.637, 119.557, 90.00, 91.15, 90.00
R / Rfree (%)	23.7 / 27.2

The binding sites of Chlorine atom in the Crystal Structure of Acyl-Coa Dehydrogenase (pdb code 2cx9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Acyl-Coa Dehydrogenase, PDB code: 2cx9:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of Acyl-Coa Dehydrogenase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Acyl-Coa Dehydrogenase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl602 b:48.2 occ:1.00 O A:HOH666 3.3 42.1 1.0 N A:GLU7 3.6 34.8 1.0 CA A:GLU6 3.9 38.5 1.0 CB A:GLU6 3.9 40.9 1.0 C A:GLU6 4.3 37.0 1.0 CG A:GLU7 4.3 39.9 1.0 OE2 A:GLU7 4.3 41.7 1.0 CG A:GLU6 4.4 42.9 1.0 CB A:GLU7 4.4 39.2 1.0 CD A:GLU7 4.6 38.4 1.0 CA A:GLU7 4.7 37.7 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of Acyl-Coa Dehydrogenase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Acyl-Coa Dehydrogenase within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl604 b:47.2 occ:1.00 N B:GLU7 3.8 29.9 1.0 CA B:GLU6 4.1 30.9 1.0 O B:HOH756 4.1 36.0 1.0 O B:HOH676 4.1 33.3 1.0 CB B:GLU6 4.2 33.7 1.0 OE2 B:GLU7 4.4 38.0 1.0 CG B:GLU7 4.4 32.8 1.0 C B:GLU6 4.5 29.4 1.0 CD B:GLU7 4.5 33.5 1.0 CG B:GLU6 4.5 38.8 1.0 CB B:GLU7 4.6 31.9 1.0 CA B:GLU7 4.9 31.5 1.0 O B:PHE5 5.0 34.1 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of Acyl-Coa Dehydrogenase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Acyl-Coa Dehydrogenase within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl601 b:42.6 occ:1.00 N D:SER67 3.5 26.6 1.0 O D:HOH677 3.5 36.5 1.0 OG D:SER67 3.6 27.9 1.0 CD2 D:LEU70 3.8 28.6 1.0 CB D:SER67 3.9 27.6 1.0 CA D:LEU66 4.1 27.2 1.0 C D:LEU66 4.3 27.4 1.0 CB D:LEU70 4.3 25.4 1.0 CA D:SER67 4.4 27.8 1.0 CB D:LEU66 4.4 27.1 1.0 CD2 D:LEU66 4.7 30.5 1.0 CG D:LEU70 4.7 28.3 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of Acyl-Coa Dehydrogenase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Acyl-Coa Dehydrogenase within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl603 b:47.9 occ:1.00 CG D:GLU7 3.8 36.4 1.0 N D:GLU7 3.8 35.3 1.0 CA D:GLU6 4.0 37.6 1.0 CB D:GLU6 4.2 38.2 1.0 C D:GLU6 4.5 36.5 1.0 CG D:GLU6 4.6 42.0 1.0 CB D:GLU7 4.6 33.5 1.0 CD D:GLU7 4.6 36.3 1.0 CA D:GLU7 4.8 35.5 1.0 O D:PHE5 4.9 37.7 1.0

K.Murayama, T.Kinebuchi, M.Shirouzu, S.Yokoyama. Crystal Structure of Acyl-Coa Dehydrogenase To Be Published.