Chlorine in PDB 2f26: Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant

All present enzymatic activity of Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant:
3.2.1.18;

The structure of Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant, PDB code: 2f26 was solved by L.M.G.Chavas, R.Kato, P.Fusi, C.Tringali, B.Venerando, G.Tettamanti, E.Monti, S.Wakatsuki, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	72.55 / 1.58
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	145.650, 145.650, 64.210, 90.00, 90.00, 120.00
R / Rfree (%)	20.9 / 22

The binding sites of Chlorine atom in the Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant (pdb code 2f26). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant, PDB code: 2f26:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:26.5 occ:1.00 O A:HOH1052 3.1 30.9 1.0 N A:GLY30 3.1 24.0 1.0 N A:GLN31 3.3 24.3 1.0 CA A:GLY30 3.6 24.5 1.0 CB A:LEU28 3.6 22.0 1.0 O A:HOH1243 3.6 45.8 1.0 CG A:GLN31 3.8 31.2 1.0 C A:LEU28 3.9 20.1 1.0 N A:PRO29 3.9 21.0 1.0 C A:GLY30 4.0 24.9 1.0 CA A:LEU28 4.0 20.4 1.0 CE1 A:TYR91 4.0 28.1 1.0 CD A:PRO29 4.0 21.8 1.0 CB A:GLN31 4.2 27.4 1.0 C A:PRO29 4.2 22.8 1.0 O A:LEU28 4.3 20.5 1.0 ND1 A:HIS132 4.4 32.0 1.0 OH A:TYR91 4.4 30.9 1.0 CZ A:TYR91 4.4 27.9 1.0 CA A:GLN31 4.4 24.7 1.0 CG A:PRO29 4.5 23.7 1.0 CA A:PRO29 4.6 22.9 1.0 CG A:LEU28 4.6 23.7 1.0 CD1 A:TYR91 4.6 27.6 1.0 CE1 A:HIS132 4.7 33.5 1.0 CD2 A:LEU28 4.8 22.3 1.0 CD A:GLN31 4.9 34.3 1.0 CD1 A:LEU28 4.9 24.2 1.0 OE1 A:GLN31 4.9 36.9 1.0

L.M.G.Chavas, R.Kato, P.Fusi, C.Tringali, B.Venerando, G.Tettamanti, E.Monti, S.Wakatsuki. Crystal Structure of the Human Sialidase NEU2 E111Q-Q112E Double Mutant To Be Published.