Chlorine in PDB 2fcy: Hiv-1 Dis Kissing-Loop in Complex with Neomycin

The structure of Hiv-1 Dis Kissing-Loop in Complex with Neomycin, PDB code: 2fcy was solved by E.Ennifar, J.C.Paillart, R.Marquet, P.Dumas, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.22 / 2.20
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	27.105, 113.702, 96.165, 90.00, 90.00, 90.00
R / Rfree (%)	23.5 / 25.3

The structure of Hiv-1 Dis Kissing-Loop in Complex with Neomycin also contains other interesting chemical elements:

Bromine	(Br)	2 atoms
Potassium	(K)	6 atoms

The binding sites of Chlorine atom in the Hiv-1 Dis Kissing-Loop in Complex with Neomycin (pdb code 2fcy). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Hiv-1 Dis Kissing-Loop in Complex with Neomycin, PDB code: 2fcy:

Chlorine binding site 1 out of 1 in the Hiv-1 Dis Kissing-Loop in Complex with Neomycin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hiv-1 Dis Kissing-Loop in Complex with Neomycin within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2004 b:46.6 occ:0.67 N6 B:A8 3.0 23.4 1.0 O B:HOH2007 3.2 41.7 1.0 O B:HOH2011 3.4 39.4 1.0 C6 B:A8 3.9 21.4 1.0 N1 B:A8 4.0 21.2 1.0 N1 B:A9 4.1 11.6 1.0 N6 B:A9 4.7 11.7 1.0 C6 B:A9 4.8 11.8 1.0 C2 B:A9 4.8 14.8 1.0

E.Ennifar, J.C.Paillart, A.Bodlenner, P.Walter, J.-M.Weibel, A.-M.Aubertin, P.Pale, P.Dumas, R.Marquet. Targeting the Dimerization Initiation Site of Hiv-1 Rna with Aminoglycosides: From Crystal to Cell. Nucleic Acids Res. V. 34 2328 2006.
ISSN: ISSN 0305-1048
PubMed: 16679451
DOI: 10.1093/NAR/GKL317