Chlorine in PDB 2fij: Crystal Structure Analysis of the A-Dna Decamer Gcgt-2'Omea-Au-Acgc, with Incorporated 2'-O-Methylated-Adenosine (2'Omea) and Arabino- Uridine (Au)

The structure of Crystal Structure Analysis of the A-Dna Decamer Gcgt-2'Omea-Au-Acgc, with Incorporated 2'-O-Methylated-Adenosine (2'Omea) and Arabino- Uridine (Au), PDB code: 2fij was solved by M.Egli, F.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	33.37 / 1.19
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	32.277, 32.469, 66.749, 90.00, 90.00, 90.00
R / Rfree (%)	15.7 / 16.9

The structure of Crystal Structure Analysis of the A-Dna Decamer Gcgt-2'Omea-Au-Acgc, with Incorporated 2'-O-Methylated-Adenosine (2'Omea) and Arabino- Uridine (Au) also contains other interesting chemical elements:

Cobalt

(Co)

3 atoms

The binding sites of Chlorine atom in the Crystal Structure Analysis of the A-Dna Decamer Gcgt-2'Omea-Au-Acgc, with Incorporated 2'-O-Methylated-Adenosine (2'Omea) and Arabino- Uridine (Au) (pdb code 2fij). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure Analysis of the A-Dna Decamer Gcgt-2'Omea-Au-Acgc, with Incorporated 2'-O-Methylated-Adenosine (2'Omea) and Arabino- Uridine (Au), PDB code: 2fij:

Chlorine binding site 1 out of 1 in the Crystal Structure Analysis of the A-Dna Decamer Gcgt-2'Omea-Au-Acgc, with Incorporated 2'-O-Methylated-Adenosine (2'Omea) and Arabino- Uridine (Au)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure Analysis of the A-Dna Decamer Gcgt-2'Omea-Au-Acgc, with Incorporated 2'-O-Methylated-Adenosine (2'Omea) and Arabino- Uridine (Au) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl101 b:13.2 occ:1.00 N5 A:NCO2213 3.2 17.6 1.0 N3 B:NCO2212 3.2 16.9 1.0 N6 B:A2M15 3.3 11.3 1.0 N6 A:A2M5 3.3 11.6 1.0 N6 B:NCO2212 3.5 17.4 1.0 N1 A:NCO2213 3.5 17.7 1.0 N4 B:NCO2212 3.6 15.3 1.0 N2 A:NCO2213 3.6 15.7 1.0 O4 B:UAR16 3.9 13.2 1.0 O4 A:UAR6 4.0 13.0 1.0 O B:HOH174 4.0 31.8 0.5 C7 B:DT14 4.0 12.1 1.0 C7 A:DT4 4.1 12.2 1.0 O4 B:DT14 4.1 12.2 1.0 CO B:NCO2212 4.2 14.9 1.0 CO A:NCO2213 4.2 14.2 1.0 O4 A:DT4 4.2 12.4 1.0 O A:HOH160 4.4 29.8 1.0 C6 B:A2M15 4.6 10.8 1.0 C6 A:A2M5 4.6 11.1 1.0 O A:HOH140 4.7 35.8 1.0 C4 B:DT14 4.8 11.5 1.0 C4 A:DT4 4.8 10.7 1.0 C5 B:DT14 4.8 11.5 1.0 C5 A:DT4 4.9 11.6 1.0 O B:HOH205 5.0 35.1 1.0

F.Li, S.Sarkhel, C.J.Wilds, Z.Wawrzak, T.P.Prakash, M.Manoharan, M.Egli. 2'-Fluoroarabino- and Arabinonucleic Acid Show Different Conformations, Resulting in Deviating Rna Affinities and Processing of Their Heteroduplexes with Rna By Rnase H. Biochemistry V. 45 4141 2006.
ISSN: ISSN 0006-2960
PubMed: 16566588
DOI: 10.1021/BI052322R