Chlorine in PDB 2g0n: The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride

The structure of The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride, PDB code: 2g0n was solved by E.Ugochukwu, X.Yang, Y.Zao, J.Elkins, C.Gileadi, N.Burgess, S.Colebrook, O.Gileadi, O.Fedorov, G.Bunkoczi, M.Sundstrom, C.Arrowsmith, J.Weigelt, A.Edwards, F.Von Delft, D.Doyle, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	22.43 / 1.90
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	53.932, 80.841, 84.563, 90.00, 90.00, 90.00
R / Rfree (%)	16.5 / 22.1

The structure of The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride (pdb code 2g0n). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride, PDB code: 2g0n:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl702 b:36.8 occ:1.00 O A:HOH844 2.8 47.8 1.0 N A:GLY60 3.1 37.2 1.0 NZ A:LYS16 3.1 35.6 1.0 NE2 A:GLN61 3.2 41.9 1.0 O3B A:GDP501 3.5 28.0 1.0 CA A:GLY12 3.7 37.8 1.0 OE1 A:GLN61 3.7 41.4 1.0 CD A:GLN61 3.9 36.5 1.0 CE A:LYS16 4.0 34.9 1.0 CA A:ALA59 4.0 37.0 1.0 CA A:GLY60 4.0 38.9 1.0 C A:ALA59 4.0 38.9 1.0 O A:HOH788 4.0 32.8 1.0 O A:THR58 4.1 37.2 1.0 PB A:GDP501 4.3 28.8 1.0 N A:GLY12 4.3 32.7 1.0 O2B A:GDP501 4.4 26.2 1.0 O1B A:GDP501 4.4 22.9 1.0 CE2 A:PHE37 4.5 66.5 1.0 MG A:MG602 4.5 37.5 1.0 N A:ALA13 4.6 38.5 1.0 C A:GLY12 4.7 39.3 1.0 O A:ASP11 4.7 32.5 1.0 C A:ASP11 4.8 33.0 1.0 C A:GLY60 4.8 40.1 1.0 N A:GLN61 4.8 39.7 1.0 CB A:ALA59 4.9 37.7 1.0 C A:THR58 4.9 36.8 1.0 N A:ALA59 4.9 33.0 1.0 O A:GLY10 5.0 33.8 1.0

Chlorine binding site 2 out of 3 in the The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl703 b:72.1 occ:1.00 O A:HOH751 3.5 31.3 1.0 O A:SER151 3.7 37.6 1.0 O A:HOH717 3.8 32.1 1.0 CD A:ARG147 4.0 70.7 1.0 CB A:ALA146 4.1 32.4 1.0 CD1 A:LEU143 4.2 42.3 1.0 N A:LYS153 4.3 33.7 1.0 CA A:LYS153 4.4 32.2 1.0 N A:TYR154 4.4 32.1 1.0 C A:VAL152 4.4 36.8 1.0 O A:VAL152 4.5 37.3 1.0 C A:LYS153 4.5 34.7 1.0 C A:SER151 4.5 36.8 1.0 C A:ALA146 4.6 35.3 1.0 N A:ARG147 4.6 35.1 1.0 NH1 A:ARG147 4.7 83.0 1.0 CG A:ARG147 4.8 54.1 1.0 O A:ALA146 4.8 32.8 1.0 CB A:TYR154 4.9 29.9 1.0 CB A:SER151 5.0 35.9 0.5 CA A:ARG147 5.0 36.3 1.0 CB A:SER151 5.0 33.1 0.5

Chlorine binding site 3 out of 3 in the The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl701 b:39.5 occ:1.00 O B:HOH815 3.0 36.7 1.0 N B:GLY60 3.1 37.3 1.0 NZ B:LYS16 3.2 34.8 1.0 NE2 B:GLN61 3.3 53.4 1.0 O3B B:GDP502 3.6 31.1 1.0 OE1 B:GLN61 3.7 42.2 1.0 CA B:GLY12 3.7 37.3 1.0 O B:HOH742 3.9 33.4 1.0 CD B:GLN61 3.9 50.3 1.0 CE B:LYS16 3.9 35.1 1.0 CA B:ALA59 4.0 36.4 1.0 CA B:GLY60 4.0 40.5 1.0 O B:THR58 4.0 38.5 1.0 C B:ALA59 4.0 40.2 1.0 CE2 B:PHE37 4.3 67.1 1.0 N B:GLY12 4.3 34.0 1.0 O2B B:GDP502 4.3 26.2 1.0 PB B:GDP502 4.4 28.6 1.0 MG B:MG601 4.4 37.4 1.0 O1B B:GDP502 4.5 26.5 1.0 O B:ASP11 4.6 32.1 1.0 N B:ALA13 4.6 38.8 1.0 C B:ASP11 4.7 32.3 1.0 C B:GLY12 4.7 39.1 1.0 N B:GLN61 4.8 32.1 1.0 C B:GLY60 4.8 40.5 1.0 CB B:ALA59 4.9 36.5 1.0 C B:THR58 4.9 38.5 1.0 O B:GLY10 4.9 33.4 1.0 CZ B:PHE37 4.9 62.4 1.0 N B:ALA59 4.9 39.1 1.0

E.Ugochukwu, X.Yang, Y.Zao, J.Elkins, C.Gileadi, N.Burgess, S.Colebrook, O.Gileadi, O.Fedorov, G.Bunkoczi, M.Sundstrom, C.Arrowsmith, J.Weigelt, A.Edwards, F.Von Delft, D.Doyle. The Crystal Structure of the Human RAC3 in Complex with Gdp and Chloride To Be Published.