Chlorine in PDB 2gnn: Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E

The structure of Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E, PDB code: 2gnn was solved by A.E.Prota, M.Pieren, A.Wagner, D.Kostrewa, F.K.Winkler, K.Ballmer-Hofer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.48 / 2.30
Space group	P 41 2 2
Cell size a, b, c (Å), α, β, γ (°)	98.600, 98.600, 240.000, 90.00, 90.00, 90.00
R / Rfree (%)	22.3 / 24.7

The binding sites of Chlorine atom in the Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E (pdb code 2gnn). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E, PDB code: 2gnn:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl702 b:87.4 occ:1.00 NH1 A:ARG107 3.7 64.1 1.0 NH2 A:ARG107 3.7 70.3 1.0 O A:HOH1013 3.8 33.8 1.0 CG A:GLU67 4.1 70.1 1.0 CZ A:ARG107 4.2 70.1 1.0 OE2 A:GLU67 4.4 87.1 1.0 CD A:GLU67 4.4 74.0 1.0 O A:HOH1016 4.7 45.1 1.0 O A:HOH1015 4.8 41.2 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl704 b:81.0 occ:1.00 O C:HOH913 3.6 35.0 1.0 NH2 C:ARG107 3.6 68.3 1.0 NH1 C:ARG107 3.7 68.5 1.0 CG C:GLU67 3.9 72.0 1.0 CZ C:ARG107 4.1 66.5 1.0 CD C:GLU67 4.3 79.7 1.0 OE2 C:GLU67 4.4 82.3 1.0 O C:HOH918 4.8 41.3 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Orf Virus NZ2 Variant of Vegf-E within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl705 b:84.9 occ:1.00 O C:HOH931 3.1 65.5 1.0 OG C:SER18 3.5 63.5 1.0 N C:TRP17 4.0 58.6 1.0 N C:SER18 4.0 58.0 1.0 O D:HOH1021 4.0 70.7 1.0 CB C:SER18 4.3 59.6 1.0 CB C:TRP17 4.4 60.0 1.0 C C:GLY16 4.5 58.1 1.0 CA C:GLY16 4.5 60.2 1.0 CA C:TRP17 4.6 58.4 1.0 CA C:SER18 4.8 58.2 1.0 C C:TRP17 4.8 57.9 1.0

M.Pieren, A.E.Prota, C.Ruch, D.Kostrewa, A.Wagner, K.Biedermann, F.K.Winkler, K.Ballmer-Hofer. Crystal Structure of the Orf Virus NZ2 Variant of Vascular Endothelial Growth Factor-E. Implications For Receptor Specificity. J.Biol.Chem. V. 281 19578 2006.
ISSN: ISSN 0021-9258
PubMed: 16672228
DOI: 10.1074/JBC.M601842200