Chlorine in PDB 2h00: Human Methyltransferase 10 Domain Containing Protein

The structure of Human Methyltransferase 10 Domain Containing Protein, PDB code: 2h00 was solved by J.R.Min, H.Wu, H.Zeng, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	115.47 / 2.00
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	133.737, 133.737, 78.833, 90.00, 90.00, 120.00
R / Rfree (%)	22.1 / 27.4

The binding sites of Chlorine atom in the Human Methyltransferase 10 Domain Containing Protein (pdb code 2h00). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Methyltransferase 10 Domain Containing Protein, PDB code: 2h00:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Methyltransferase 10 Domain Containing Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Methyltransferase 10 Domain Containing Protein within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl401 b:58.5 occ:1.00 ND2 B:ASN147 3.9 41.2 1.0 NE B:ARG245 3.9 49.0 1.0 NZ C:LYS10 3.9 38.5 1.0 NH2 B:ARG245 3.9 52.7 1.0 CE C:LYS10 4.0 37.7 1.0 NH2 B:ARG45 4.2 41.1 1.0 CD C:LYS10 4.3 40.1 1.0 OD1 B:ASN147 4.3 43.8 1.0 CZ B:ARG245 4.4 51.8 1.0 CG B:ASN147 4.6 41.1 1.0 CD2 B:LEU38 4.8 35.6 1.0 CD1 B:LEU38 4.9 40.9 1.0 NH1 B:ARG45 4.9 40.4 1.0 CD B:ARG245 5.0 45.6 1.0 CZ B:ARG45 5.0 39.5 1.0

Chlorine binding site 2 out of 2 in the Human Methyltransferase 10 Domain Containing Protein


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Methyltransferase 10 Domain Containing Protein within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl402 b:68.4 occ:1.00 O C:HOH451 2.3 63.1 1.0 NE C:ARG245 3.8 42.9 1.0 NZ B:LYS10 3.8 49.0 1.0 ND2 C:ASN147 3.9 36.3 1.0 CD B:LYS10 3.9 45.1 1.0 CE B:LYS10 3.9 47.8 1.0 NH2 C:ARG245 4.0 45.8 1.0 OD1 C:ASN147 4.0 37.8 1.0 NH2 B:ARG242 4.3 64.0 1.0 CZ C:ARG245 4.4 43.5 1.0 CG C:ASN147 4.4 35.8 1.0 NH1 B:ARG242 4.5 61.2 1.0 NH2 C:ARG45 4.6 39.3 1.0 CD2 C:LEU38 4.7 36.5 1.0 CD C:ARG245 4.8 37.7 1.0 CG B:LYS10 4.8 45.7 1.0 CZ B:ARG242 4.9 62.7 1.0 CD1 C:LEU38 4.9 36.5 1.0

H.Wu, J.Min, H.Zeng, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov. The Crystal Structure of Human Methyltransferase 10 Domain Containing Protein. To Be Published.