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Chlorine in PDB 2hpm: Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III

Enzymatic activity of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III

All present enzymatic activity of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III:
2.7.7.7;

Protein crystallography data

The structure of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III, PDB code: 2hpm was solved by S.Bailey, R.A.Wing, T.A.Steitz, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 3.70
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 174.442, 185.724, 125.836, 90.00, 90.00, 90.00
R / Rfree (%) 24 / 31.1

Other elements in 2hpm:

The structure of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III (pdb code 2hpm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III, PDB code: 2hpm:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 2hpm

Go back to Chlorine Binding Sites List in 2hpm
Chlorine binding site 1 out of 2 in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1225

b:89.7
occ:1.00
CL A:CL1226 3.8 93.9 1.0
NH1 A:ARG711 3.9 99.1 1.0
O A:GLY739 4.1 0.0 1.0
CZ A:PHE808 4.2 0.5 1.0
NH2 A:ARG711 4.3 0.9 1.0
CZ A:ARG711 4.6 0.7 1.0
CE1 A:PHE808 4.9 0.8 1.0

Chlorine binding site 2 out of 2 in 2hpm

Go back to Chlorine Binding Sites List in 2hpm
Chlorine binding site 2 out of 2 in the Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Eubacterial and Eukaryotic Replicative Dna Polymerases Are Not Homologous: X-Ray Structure of Dna Polymerase III within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1226

b:93.9
occ:1.00
CL A:CL1225 3.8 89.7 1.0
SD A:MET804 3.8 0.5 1.0
O A:GLY739 4.0 0.0 1.0
CE1 A:PHE723 4.2 0.1 1.0
CD2 A:TYR720 4.6 0.0 1.0
CE2 A:TYR720 4.6 0.7 1.0
CD1 A:PHE723 5.0 0.4 1.0

Reference:

S.Bailey, R.A.Wing, T.A.Steitz. The Structure of T. Aquaticus Dna Polymerase III Is Distinct From Eukaryotic Replicative Dna Polymerases. Cell(Cambridge,Mass.) V. 126 893 2006.
ISSN: ISSN 0092-8674
PubMed: 16959569
DOI: 10.1016/J.CELL.2006.07.027
Page generated: Sat Dec 12 09:07:33 2020

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