Chlorine in PDB 2i54: Phosphomannomutase From Leishmania Mexicana

All present enzymatic activity of Phosphomannomutase From Leishmania Mexicana:
5.4.2.8;

The structure of Phosphomannomutase From Leishmania Mexicana, PDB code: 2i54 was solved by B.J.Smith, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.80 / 2.10
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	92.413, 92.413, 173.249, 90.00, 90.00, 120.00
R / Rfree (%)	18.9 / 23

The structure of Phosphomannomutase From Leishmania Mexicana also contains other interesting chemical elements:

Magnesium

(Mg)

3 atoms

The binding sites of Chlorine atom in the Phosphomannomutase From Leishmania Mexicana (pdb code 2i54). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Phosphomannomutase From Leishmania Mexicana, PDB code: 2i54:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Phosphomannomutase From Leishmania Mexicana


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Phosphomannomutase From Leishmania Mexicana within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:37.4 occ:0.50 N A:PHE118 3.1 47.3 1.0 N A:VAL119 3.5 49.9 1.0 CA A:THR117 3.8 46.4 1.0 CB A:PHE118 3.8 47.9 1.0 CD1 A:PHE118 3.9 49.1 1.0 CA A:PHE118 3.9 48.6 1.0 C A:THR117 4.0 47.0 1.0 O A:VAL119 4.0 49.4 1.0 N A:THR117 4.1 46.0 1.0 C A:PHE118 4.2 49.0 1.0 CG A:PHE118 4.3 47.9 1.0 CA A:VAL119 4.5 49.2 1.0 C A:VAL119 4.6 49.3 1.0 CD2 A:LEU103 4.7 49.3 1.0 CB A:VAL119 4.7 49.4 1.0 CE1 A:PHE118 5.0 47.6 1.0

Chlorine binding site 2 out of 2 in the Phosphomannomutase From Leishmania Mexicana


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Phosphomannomutase From Leishmania Mexicana within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1002 b:36.2 occ:1.00 N C:PHE118 3.1 46.7 1.0 N B:PHE118 3.1 47.2 1.0 N B:VAL119 3.4 48.5 1.0 N C:VAL119 3.5 48.0 1.0 CA B:THR117 3.7 46.6 1.0 CA C:THR117 3.8 47.0 1.0 CD2 B:PHE118 3.9 47.5 1.0 C B:THR117 3.9 46.5 1.0 CD2 C:PHE118 3.9 45.8 1.0 C C:THR117 3.9 47.9 1.0 CA B:PHE118 3.9 47.7 1.0 CA C:PHE118 3.9 47.6 1.0 CB B:PHE118 4.0 48.0 1.0 CB C:PHE118 4.0 47.1 1.0 N C:THR117 4.0 46.9 1.0 N B:THR117 4.0 45.7 1.0 O B:VAL119 4.0 49.2 1.0 O C:VAL119 4.1 48.6 1.0 C B:PHE118 4.2 48.5 1.0 C C:PHE118 4.2 48.2 1.0 CG B:PHE118 4.4 47.5 1.0 CG C:PHE118 4.4 46.0 1.0 CA B:VAL119 4.4 48.8 1.0 CA C:VAL119 4.5 48.4 1.0 C B:VAL119 4.6 48.8 1.0 C C:VAL119 4.6 48.3 1.0 CB B:VAL119 4.6 49.5 1.0 CD2 B:LEU103 4.7 51.7 1.0 CB C:VAL119 4.8 48.7 1.0 CD2 C:LEU103 4.8 54.3 1.0 CE2 B:PHE118 4.9 48.3 1.0 CE2 C:PHE118 4.9 46.6 1.0

L.Kedzierski, R.L.Malby, B.J.Smith, M.A.Perugini, A.N.Hodder, T.Ilg, P.M.Colman, E.Handman. Structure of Leishmania Mexicana Phosphomannomutase Highlights Similarities with Human Isoforms J.Mol.Biol. V. 363 215 2006.
ISSN: ISSN 0022-2836
PubMed: 16963079
DOI: 10.1016/J.JMB.2006.08.023