Chlorine in PDB 2i55: Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana

All present enzymatic activity of Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana:
5.4.2.8;

The structure of Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana, PDB code: 2i55 was solved by B.J.Smith, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.70 / 2.90
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	92.224, 92.224, 172.824, 90.00, 90.00, 120.00
R / Rfree (%)	19.2 / 26.8

The structure of Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana also contains other interesting chemical elements:

Magnesium

(Mg)

5 atoms

The binding sites of Chlorine atom in the Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana (pdb code 2i55). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana, PDB code: 2i55:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:52.6 occ:0.50 N A:VAL119 3.0 64.6 1.0 O A:VAL119 3.1 64.2 1.0 N A:PHE118 3.2 64.2 1.0 CA A:VAL119 3.7 64.5 1.0 C A:VAL119 3.7 64.1 1.0 CB A:VAL119 3.8 64.8 1.0 C A:PHE118 3.9 64.5 1.0 CA A:PHE118 3.9 64.5 1.0 C A:THR117 4.0 64.1 1.0 CA A:THR117 4.0 64.3 1.0 CB A:PHE118 4.2 64.6 1.0 CD1 A:PHE118 4.5 64.7 1.0 CD2 A:LEU103 4.5 63.4 1.0 N A:THR117 4.6 64.3 1.0 CG2 A:VAL119 4.7 65.0 1.0 CG A:PHE118 4.8 64.7 1.0 CG1 A:VAL119 4.9 65.0 1.0 N A:GLU120 5.0 64.0 1.0

Chlorine binding site 2 out of 2 in the Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Complex of Glucose-1,6-Bisphosphate with Phosphomannomutase From Leishmania Mexicana within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1002 b:54.2 occ:1.00 N C:PHE118 3.0 62.5 1.0 N B:PHE118 3.1 64.1 1.0 N C:VAL119 3.5 62.3 1.0 N B:VAL119 3.6 64.5 1.0 CA C:THR117 3.7 61.9 1.0 CA B:THR117 3.8 63.3 1.0 C C:THR117 3.8 62.2 1.0 CD2 C:PHE118 3.8 64.6 1.0 CA C:PHE118 3.8 62.6 1.0 CD2 B:PHE118 3.9 63.9 1.0 O C:VAL119 3.9 63.4 1.0 C B:THR117 3.9 63.7 1.0 CB C:PHE118 3.9 63.3 1.0 CA B:PHE118 3.9 64.2 1.0 CB B:PHE118 3.9 64.2 1.0 N B:THR117 4.1 63.2 1.0 C C:PHE118 4.2 62.2 1.0 N C:THR117 4.2 61.9 1.0 O B:VAL119 4.3 65.0 1.0 C B:PHE118 4.3 64.4 1.0 CG C:PHE118 4.3 63.8 1.0 CG B:PHE118 4.4 63.4 1.0 CA C:VAL119 4.4 62.7 1.0 C C:VAL119 4.5 62.9 1.0 CD2 B:LEU103 4.5 62.4 1.0 CB C:VAL119 4.6 62.6 1.0 CA B:VAL119 4.6 64.6 1.0 C B:VAL119 4.7 64.6 1.0 CB B:VAL119 4.9 64.7 1.0 CE2 C:PHE118 4.9 64.4 1.0 CD2 C:LEU103 4.9 62.0 1.0 CE2 B:PHE118 4.9 64.1 1.0 O C:THR117 5.0 62.2 1.0

L.Kedzierski, R.L.Malby, B.J.Smith, M.A.Perugini, A.N.Hodder, T.Ilg, P.M.Colman, E.Handman. Structure of Leishmania Mexicana Phosphomannomutase Highlights Similarities with Human Isoforms J.Mol.Biol. V. 363 215 2006.
ISSN: ISSN 0022-2836
PubMed: 16963079
DOI: 10.1016/J.JMB.2006.08.023