Chlorine in PDB 2ihd: Crystal Structure of Human Regulator of G-Protein Signaling 8, RGS8

The structure of Crystal Structure of Human Regulator of G-Protein Signaling 8, RGS8, PDB code: 2ihd was solved by A.P.Turnbull, E.Papagrigoriou, E.Ugochukwu, E.Salah, C.Gileadi, N.Burgess, C.Bhatia, O.Gileadi, J.Bray, J.Elkins, F.Von Delft, J.Weigelt, A.Edwards, C.Arrowsmith, M.Sundstrom, D.A.Doyle, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.50 / 1.70
Space group	I 41
Cell size a, b, c (Å), α, β, γ (°)	65.967, 65.967, 76.377, 90.00, 90.00, 90.00
R / Rfree (%)	17.5 / 21.1

The binding sites of Chlorine atom in the Crystal Structure of Human Regulator of G-Protein Signaling 8, RGS8 (pdb code 2ihd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Regulator of G-Protein Signaling 8, RGS8, PDB code: 2ihd:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Regulator of G-Protein Signaling 8, RGS8


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Regulator of G-Protein Signaling 8, RGS8 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:20.1 occ:1.00 O A:HOH324 3.1 44.2 1.0 O A:HOH315 3.3 37.6 1.0 O A:HOH210 3.4 30.4 1.0 NE1 A:TRP86 3.5 12.1 1.0 CB A:HIS151 3.9 4.8 1.0 CG A:HIS151 4.0 8.2 1.0 CG A:GLN147 4.0 7.7 1.0 CD A:GLN147 4.1 7.6 1.0 CD2 A:HIS151 4.1 10.9 1.0 O A:GLN147 4.2 6.9 1.0 CA A:GLY148 4.3 7.9 1.0 OE1 A:GLN147 4.3 9.8 1.0 N A:GLY148 4.3 6.7 1.0 C A:GLN147 4.3 5.9 1.0 CD1 A:TRP86 4.4 11.5 1.0 NE2 A:GLN147 4.5 10.2 1.0 CE2 A:TRP86 4.5 12.6 1.0 O A:HOH261 4.7 35.9 1.0 ND1 A:HIS151 4.7 11.6 1.0 CB A:GLN147 4.7 9.1 1.0 CZ2 A:TRP86 4.8 12.9 1.0 NE2 A:HIS151 4.9 7.8 1.0 O A:HOH332 5.0 51.0 1.0

M.Soundararajan, F.S.Willard, A.J.Kimple, A.P.Turnbull, L.J.Ball, G.A.Schoch, C.Gileadi, O.Y.Fedorov, E.F.Dowler, V.A.Higman, S.Q.Hutsell, M.Sundstrom, D.A.Doyle, D.P.Siderovski. Structural Diversity in the Rgs Domain and Its Interaction with Heterotrimeric G Protein Alpha-Subunits. Proc.Natl.Acad.Sci.Usa V. 105 6457 2008.
ISSN: ISSN 0027-8424
PubMed: 18434541
DOI: 10.1073/PNAS.0801508105