Chlorine in PDB 2ivd: Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen

All present enzymatic activity of Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen:
1.3.3.4;

The structure of Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen, PDB code: 2ivd was solved by H.R.Corradi, A.V.Corrigall, E.Boix, C.G.Mohan, E.D.Sturrock, P.N.Meissner, K.R.Acharya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.39 / 2.3
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	148.918, 148.918, 131.924, 90.00, 90.00, 90.00
R / Rfree (%)	23.4 / 28.3

The structure of Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen also contains other interesting chemical elements:

Fluorine

(F)

6 atoms

The binding sites of Chlorine atom in the Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen (pdb code 2ivd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen, PDB code: 2ivd:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1465 b:49.6 occ:1.00 CL1 A:ACJ1465 0.0 49.6 1.0 C4 A:ACJ1465 1.8 50.1 1.0 C3 A:ACJ1465 2.8 49.9 1.0 C7 A:ACJ1465 2.8 50.4 1.0 O1 A:ACJ1465 3.0 50.4 1.0 C8 A:ACJ1465 3.6 50.1 1.0 CB A:MET365 3.6 27.4 1.0 O A:THR166 3.7 24.7 1.0 CG A:MET365 3.8 28.3 1.0 CB A:LEU342 3.8 30.8 1.0 CD2 A:LEU332 4.0 20.6 1.0 C2 A:ACJ1465 4.1 50.5 1.0 CG2 A:THR166 4.1 24.5 1.0 C6 A:ACJ1465 4.1 49.8 1.0 CA A:GLY167 4.1 24.6 1.0 C9 A:ACJ1465 4.2 50.4 1.0 C A:THR166 4.2 24.5 1.0 C A:LEU342 4.2 30.7 1.0 C12 A:ACJ1465 4.2 49.9 1.0 O A:LEU342 4.3 30.3 1.0 N A:GLY167 4.4 24.3 1.0 N A:GLY343 4.4 30.7 1.0 CD1 A:LEU342 4.6 27.3 1.0 C5 A:ACJ1465 4.6 50.0 1.0 CA A:LEU342 4.7 30.9 1.0 CA A:GLY343 4.7 30.4 1.0 CG A:LEU342 4.8 29.2 1.0 C A:GLY167 4.9 24.8 1.0 C A:GLY343 5.0 30.3 1.0 O A:GLY343 5.0 30.1 1.0

Chlorine binding site 2 out of 2 in the Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus with Acifluorfen within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1468 b:54.5 occ:1.00 CL1 B:ACJ1468 0.0 54.5 1.0 C4 B:ACJ1468 1.8 53.2 1.0 C3 B:ACJ1468 2.8 53.1 1.0 C7 B:ACJ1468 2.8 53.8 1.0 O1 B:ACJ1468 3.0 53.6 1.0 C8 B:ACJ1468 3.6 53.2 1.0 O B:THR166 3.6 23.3 1.0 CB B:MET365 3.7 27.8 1.0 CD2 B:LEU332 3.7 20.7 1.0 CB B:LEU342 3.8 26.2 1.0 CG B:MET365 3.8 28.5 1.0 CA B:GLY167 3.9 24.2 1.0 C2 B:ACJ1468 4.1 54.0 1.0 C6 B:ACJ1468 4.1 53.9 1.0 C B:THR166 4.1 23.6 1.0 CG2 B:THR166 4.2 22.6 1.0 C12 B:ACJ1468 4.2 53.0 1.0 C9 B:ACJ1468 4.3 53.1 1.0 N B:GLY167 4.3 23.9 1.0 C B:LEU342 4.4 26.9 1.0 O B:LEU342 4.4 26.8 1.0 CG B:LEU342 4.4 25.7 1.0 N B:GLY343 4.5 26.8 1.0 CD2 B:LEU342 4.6 22.6 1.0 C5 B:ACJ1468 4.6 54.0 1.0 CA B:LEU342 4.8 26.6 1.0 CA B:GLY343 4.8 26.7 1.0 C B:GLY167 4.9 24.9 1.0

H.R.Corradi, A.V.Corrigall, E.Boix, C.G.Mohan, E.D.Sturrock, P.N.Meissner, K.R.Acharya. Crystal Structure of Protoporphyrinogen Oxidase From Myxococcus Xanthus and Its Complex with the Inhibitor Acifluorfen. J.Biol.Chem. V. 281 38625 2006.
ISSN: ISSN 0021-9258
PubMed: 17046834
DOI: 10.1074/JBC.M606640200