Chlorine in PDB 2ixp: Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate

The structure of Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate, PDB code: 2ixp was solved by N.Leulliot, G.Vicentini, J.Jordens, S.Quevillon-Cheruel, M.Schiltz, D.Barford, H.Van Tilbeurgh, J.Goris, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.12 / 2.80
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	86.886, 86.886, 410.626, 90.00, 90.00, 120.00
R / Rfree (%)	22.9 / 30.2

The binding sites of Chlorine atom in the Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate (pdb code 2ixp). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate, PDB code: 2ixp:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1321 b:13.8 occ:1.00 O A:MET260 3.5 2.0 1.0 NH2 C:ARG99 4.2 9.1 1.0 C A:MET260 4.7 2.0 1.0 CG A:MET260 4.8 2.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the PP2A Phosphatase Activator YPA1 PTPA1 in Complex with Model Substrate within 5.0Å range: probe atom residue distance (Å) B Occ D:Cl1320 b:7.4 occ:1.00 O D:MET260 3.5 2.0 1.0 O D:GLY261 3.9 2.0 1.0 C D:MET260 4.5 2.0 1.0 CE D:MET260 4.5 5.7 1.0 SD D:MET260 5.0 5.5 1.0

N.Leulliot, G.Vicentini, J.Jordens, S.Quevillon-Cheruel, M.Schiltz, D.Barford, H.Van Tilbeurgh, J.Goris. Crystal Structure of the PP2A Phosphatase Activator: Implications For Its PP2A-Specific Ppiase Activity. Mol. Cell V. 23 413 2006.
ISSN: ISSN 1097-2765
PubMed: 16885030
DOI: 10.1016/J.MOLCEL.2006.07.008