Chlorine in PDB 2izv: Crystal Structure of Socs-4 in Complex with Elongin-B and Elongin-C at 2.55A Resolution

The structure of Crystal Structure of Socs-4 in Complex with Elongin-B and Elongin-C at 2.55A Resolution, PDB code: 2izv was solved by J.E.Debreczeni, A.Bullock, E.Papagrigoriou, A.Turnbull, A.C.W.Pike, F.Gorrec, F.Von Delft, M.Sundstrom, C.Arrowsmith, J.Weigelt, A.Edwards, S.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	77.38 / 2.55
Space group	H 3
Cell size a, b, c (Å), α, β, γ (°)	154.770, 154.770, 67.909, 90.00, 90.00, 120.00
R / Rfree (%)	17.2 / 22.3

The structure of Crystal Structure of Socs-4 in Complex with Elongin-B and Elongin-C at 2.55A Resolution also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Socs-4 in Complex with Elongin-B and Elongin-C at 2.55A Resolution (pdb code 2izv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Socs-4 in Complex with Elongin-B and Elongin-C at 2.55A Resolution, PDB code: 2izv:

Chlorine binding site 1 out of 1 in the Crystal Structure of Socs-4 in Complex with Elongin-B and Elongin-C at 2.55A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Socs-4 in Complex with Elongin-B and Elongin-C at 2.55A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1432 b:53.7 occ:1.00 CE1 A:HIS391 3.8 31.7 1.0 ND1 A:HIS391 3.9 23.3 1.0 OH A:TYR422 3.9 27.0 1.0 NE2 A:HIS391 4.0 24.1 1.0 CA A:GLY289 4.1 19.6 1.0 CG A:HIS391 4.2 13.6 1.0 N A:VAL290 4.2 25.5 1.0 O A:HOH2008 4.2 29.6 1.0 CD2 A:HIS391 4.2 26.6 1.0 O A:HOH2046 4.3 14.1 1.0 CG2 A:VAL290 4.4 11.4 1.0 OH A:TYR287 4.4 13.3 1.0 CE2 A:PHE387 4.4 23.7 1.0 CD2 A:PHE387 4.5 21.9 1.0 C A:GLY289 4.7 22.7 1.0 CZ A:PHE387 4.8 27.4 1.0 O A:HOH2061 4.8 34.8 1.0 O A:HOH2005 4.8 20.5 1.0 OD2 A:ASP312 4.9 34.8 1.0 CG A:PHE387 4.9 21.7 1.0 CB A:HIS391 5.0 21.5 1.0 CZ A:TYR422 5.0 15.7 1.0

A.N.Bullock, M.C.Rodriguez, J.E.Debreczeni, Z.Songyang, S.Knapp. Structure of the SOCS4-Elonginb/C Complex Reveals A Distinct Socs Box Interface and the Molecular Basis For Socs-Dependent Egfr Degradation. Structure V. 15 1493 2007.
ISSN: ISSN 0969-2126
PubMed: 17997974
DOI: 10.1016/J.STR.2007.09.016