Chlorine in PDB 2jam: Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G

All present enzymatic activity of Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G:
2.7.11.17;

The structure of Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G, PDB code: 2jam was solved by J.E.Debreczeni, A.Bullock, T.Keates, F.H.Niesen, E.Salah, L.Shrestha, C.Smee, F.Sobott, A.C.W.Pike, G.Bunkoczi, F.Von Delft, A.Turnbull, J.Weigelt, C.H.Arrowsmith, A.Edwards, M.Sundstrom, S.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	56.89 / 1.70
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	51.666, 53.736, 64.177, 65.45, 71.91, 73.84
R / Rfree (%)	15.5 / 23.1

The structure of Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G also contains other interesting chemical elements:

Calcium

(Ca)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G (pdb code 2jam). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G, PDB code: 2jam:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1305 b:38.3 occ:1.00 CL A:J601305 0.0 38.3 1.0 CAA A:J601305 1.7 17.4 1.0 CAD A:J601305 2.7 17.6 1.0 CAB A:J601305 2.7 19.3 1.0 OD1 A:ASP165 3.2 22.5 1.0 CB A:ASP165 3.3 17.4 1.0 CA A:ASP165 3.3 18.4 1.0 CG A:ASP165 3.4 15.2 1.0 CG2 A:VAL37 3.5 24.8 1.0 CE A:LYS52 3.5 20.2 1.0 O2 A:EDO1304 3.6 26.1 1.0 CD A:LYS52 3.7 21.9 1.0 N A:ASP165 3.8 18.2 1.0 NZ A:LYS52 3.8 24.6 1.0 CAE A:J601305 4.0 17.6 1.0 CAC A:J601305 4.0 16.2 1.0 O A:THR164 4.0 19.9 1.0 C A:THR164 4.1 15.0 1.0 CE A:MET171 4.2 27.9 1.0 OD2 A:ASP165 4.3 21.7 1.0 CG A:LYS52 4.4 21.6 1.0 C2 A:EDO1304 4.4 27.4 1.0 CAF A:J601305 4.5 17.3 1.0 C A:ASP165 4.7 16.0 1.0 CB A:VAL37 4.7 18.0 1.0 CB A:LYS52 4.8 20.8 1.0 CG1 A:VAL37 5.0 16.3 1.0 N A:PHE166 5.0 16.7 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1305 b:47.8 occ:1.00 CL B:J601305 0.0 47.8 1.0 CAA B:J601305 1.7 21.2 1.0 CAB B:J601305 2.6 23.6 1.0 CAD B:J601305 2.7 21.4 1.0 CB B:ASP165 3.3 20.8 1.0 CA B:ASP165 3.3 22.9 1.0 OD1 B:ASP165 3.4 23.2 1.0 CG2 B:VAL37 3.5 19.8 1.0 CG B:ASP165 3.6 20.1 1.0 O1 B:EDO1303 3.6 28.1 1.0 CE B:LYS52 3.7 27.8 1.0 N B:ASP165 3.8 23.9 1.0 CD B:LYS52 3.9 27.0 1.0 CAC B:J601305 3.9 24.6 1.0 NZ B:LYS52 3.9 21.5 1.0 O B:THR164 3.9 19.3 1.0 CAE B:J601305 4.0 18.9 1.0 C B:THR164 4.1 22.2 1.0 CE B:MET171 4.3 27.3 1.0 CG B:LYS52 4.4 24.4 1.0 CAF B:J601305 4.5 20.1 1.0 OD2 B:ASP165 4.5 22.5 1.0 C1 B:EDO1303 4.6 34.7 1.0 CB B:VAL37 4.7 18.7 1.0 C B:ASP165 4.7 18.1 1.0 CB B:LYS52 4.8 21.4 1.0 CG1 B:VAL37 4.9 20.6 1.0

J.E.Debreczeni, A.Bullock, T.Keates, F.H.Niesen, E.Salah, L.Shrestha, C.Smee, F.Sobott, A.C.W.Pike, G.Bunkoczi, F.Von Delft, A.Turnbull, J.Weigelt, C.H.Arrowsmith, A.Edwards, M.Sundstrom, S.Knapp. Crystal Structure of Human Calmodulin-Dependent Protein Kinase I G To Be Published.