Chlorine in PDB 2jd4: Mouse Laminin ALPHA1 Chain, Domains LG4-5

The structure of Mouse Laminin ALPHA1 Chain, Domains LG4-5, PDB code: 2jd4 was solved by D.Harrison, S.A.Hussain, A.C.Combs, J.M.Ervasti, P.D.Yurchenco, E.Hohenester, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20 / 1.9
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	70.530, 55.812, 100.986, 90.00, 98.48, 90.00
R / Rfree (%)	22.95 / 26.24

The structure of Mouse Laminin ALPHA1 Chain, Domains LG4-5 also contains other interesting chemical elements:

Magnesium

(Mg)

4 atoms

The binding sites of Chlorine atom in the Mouse Laminin ALPHA1 Chain, Domains LG4-5 (pdb code 2jd4). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Mouse Laminin ALPHA1 Chain, Domains LG4-5, PDB code: 2jd4:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Mouse Laminin ALPHA1 Chain, Domains LG4-5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Mouse Laminin ALPHA1 Chain, Domains LG4-5 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl4063 b:48.0 occ:1.00 O A:HOH2125 3.1 30.0 1.0 O A:HOH2124 3.3 36.4 1.0 CB A:SER2992 4.4 39.7 1.0 OD2 A:ASP2996 4.5 26.0 1.0 CB A:SER2994 4.5 35.1 1.0 MG A:MG4062 4.6 26.7 1.0 OG A:SER2992 4.7 42.4 1.0 N A:SER2994 4.8 36.0 1.0 CA A:SER2992 4.9 38.5 1.0 N A:THR2993 5.0 37.4 1.0

Chlorine binding site 2 out of 3 in the Mouse Laminin ALPHA1 Chain, Domains LG4-5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Mouse Laminin ALPHA1 Chain, Domains LG4-5 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl4063 b:21.6 occ:1.00 OG B:SER2992 3.1 21.3 1.0 O A:HOH2065 3.2 18.2 1.0 O A:HOH2068 3.2 23.1 1.0 N A:GLY2836 3.5 23.1 1.0 CB B:SER2992 3.6 16.9 1.0 CA A:ASN2834 3.7 21.4 1.0 CA B:SER2992 3.8 22.1 1.0 CA A:GLY2836 3.8 19.4 1.0 CD2 B:HIS2991 3.9 20.8 1.0 O B:ASN2940 4.1 20.9 1.0 N A:ILE2835 4.1 22.1 1.0 C A:ASN2834 4.1 22.6 1.0 NE2 B:HIS2991 4.2 24.3 1.0 N A:ASN2834 4.2 24.1 1.0 O A:HOH2067 4.3 19.6 1.0 O B:HIS2991 4.4 23.3 1.0 OD1 A:ASN2834 4.4 24.4 1.0 N B:SER2992 4.5 22.6 1.0 O A:HOH2041 4.6 16.3 1.0 C A:GLY2836 4.6 21.1 1.0 CA B:GLY2941 4.6 22.0 1.0 MG B:MG4062 4.6 22.2 1.0 C A:ILE2835 4.6 20.8 1.0 C B:GLY2941 4.8 24.3 1.0 C B:HIS2991 4.8 23.5 1.0 O A:GLY2836 4.8 20.9 1.0 CB A:ASN2834 4.9 23.1 1.0 O A:ASN2834 4.9 23.8 1.0 C B:ASN2940 4.9 21.2 1.0 C B:SER2992 4.9 23.8 1.0 CA A:ILE2835 5.0 20.6 1.0 N B:ALA2942 5.0 22.0 1.0

Chlorine binding site 3 out of 3 in the Mouse Laminin ALPHA1 Chain, Domains LG4-5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Mouse Laminin ALPHA1 Chain, Domains LG4-5 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl4064 b:24.0 occ:1.00 O B:HOH2093 3.2 30.1 1.0 N B:LEU2897 3.3 20.4 1.0 N B:ASP2898 3.4 22.9 1.0 NH1 B:ARG3032 3.6 21.5 1.0 CB B:LEU2897 3.7 24.8 1.0 CA B:LEU2897 3.8 19.9 1.0 CG B:ARG3032 3.9 27.9 1.0 CB B:ARG2896 4.0 19.1 1.0 CD B:ARG3032 4.0 24.2 1.0 O B:VAL2895 4.0 18.6 1.0 C B:LEU2897 4.1 23.9 1.0 O B:ASP2898 4.2 21.1 1.0 CA B:ASP2898 4.4 25.9 1.0 C B:ARG2896 4.4 20.0 1.0 CG B:LEU2897 4.5 23.9 1.0 CB B:ASP2898 4.5 32.8 1.0 CZ B:ARG3032 4.6 23.1 1.0 CA B:ARG2896 4.8 19.8 1.0 C B:ASP2898 4.8 22.8 1.0 NE B:ARG3032 4.8 22.5 1.0 NE B:ARG2896 4.9 28.7 1.0 CD1 B:LEU2897 4.9 29.9 1.0

D.Harrison, S.A.Hussain, A.C.Combs, J.M.Ervasti, P.D.Yurchenco, E.Hohenester. Crystal Structure and Cell Surface Anchorage Sites of Laminin {Alpha}1LG4-5. J.Biol.Chem. V. 282 11573 2007.
ISSN: ISSN 0021-9258
PubMed: 17307732
DOI: 10.1074/JBC.M610657200