Chlorine in PDB 2nl9: Crystal Structure of the Mcl-1:Bim BH3 Complex

The structure of Crystal Structure of the Mcl-1:Bim BH3 Complex, PDB code: 2nl9 was solved by P.E.Czabotar, P.M.Colman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.12 / 1.55
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	52.380, 70.080, 117.180, 90.00, 90.00, 90.00
R / Rfree (%)	17.3 / 20.3

The structure of Crystal Structure of the Mcl-1:Bim BH3 Complex also contains other interesting chemical elements:

Zinc

(Zn)

7 atoms

The binding sites of Chlorine atom in the Crystal Structure of the Mcl-1:Bim BH3 Complex (pdb code 2nl9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Mcl-1:Bim BH3 Complex, PDB code: 2nl9:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Mcl-1:Bim BH3 Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Mcl-1:Bim BH3 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2001 b:32.0 occ:0.50 NH1 A:ARG300 3.4 21.6 1.0 NH2 A:ARG300 3.7 29.1 1.0 CD1 A:ILE251 3.9 24.7 1.0 CG2 A:THR301 4.0 20.6 1.0 CZ A:ARG300 4.0 26.0 1.0 CG1 A:ILE251 4.4 19.8 1.0 CG2 A:ILE251 4.9 17.6 1.0

P.E.Czabotar, E.F.Lee, M.F.Van Delft, C.L.Day, B.J.Smith, D.C.Huang, W.D.Fairlie, M.G.Hinds, P.M.Colman. Structural Insights Into the Degradation of Mcl-1 Induced By BH3 Domains. Proc.Natl.Acad.Sci.Usa V. 104 6217 2007.
ISSN: ISSN 0027-8424
PubMed: 17389404
DOI: 10.1073/PNAS.0701297104