Chlorine in PDB 2nn8: Crystal Structure of Human Galectin-3 Carbohydrate-Recognition Domain with Lactose Bound, at 1.35 Angstrom Resolution

The structure of Crystal Structure of Human Galectin-3 Carbohydrate-Recognition Domain with Lactose Bound, at 1.35 Angstrom Resolution, PDB code: 2nn8 was solved by H.Blanchard, P.M.Collins, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.62 / 1.35
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	36.371, 57.800, 62.603, 90.00, 90.00, 90.00
R / Rfree (%)	16.4 / 17.5

The binding sites of Chlorine atom in the Crystal Structure of Human Galectin-3 Carbohydrate-Recognition Domain with Lactose Bound, at 1.35 Angstrom Resolution (pdb code 2nn8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Galectin-3 Carbohydrate-Recognition Domain with Lactose Bound, at 1.35 Angstrom Resolution, PDB code: 2nn8:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Galectin-3 Carbohydrate-Recognition Domain with Lactose Bound, at 1.35 Angstrom Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Galectin-3 Carbohydrate-Recognition Domain with Lactose Bound, at 1.35 Angstrom Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1001 b:12.6 occ:1.00 O A:HOH1102 2.8 31.4 1.0 O A:HOH1052 3.1 12.0 1.0 N A:LYS226 3.2 7.2 1.0 O3 A:GOL600 3.2 14.3 1.0 N A:LYS227 3.6 7.1 1.0 C3 A:GOL600 3.8 24.9 1.0 CG A:LYS227 3.8 9.1 1.0 CD A:LYS227 3.9 11.0 1.0 CA A:LYS226 4.0 8.9 1.0 C A:VAL225 4.0 8.3 1.0 CA A:VAL225 4.0 7.4 1.0 CG1 A:VAL225 4.1 9.4 1.0 CB A:LYS227 4.2 7.4 1.0 C A:LYS226 4.2 7.0 1.0 CB A:LYS226 4.3 13.1 1.0 CA A:LYS227 4.5 7.2 1.0 CE A:LYS227 4.5 14.1 1.0 O A:HOH1025 4.5 15.2 1.0 NH1 A:ARG151 4.5 8.8 1.0 CB A:VAL225 4.6 7.2 1.0 CZ A:ARG151 4.8 9.0 1.0 O A:HOH1011 4.8 9.9 1.0 O A:ARG224 4.9 8.9 1.0 NE A:ARG151 5.0 7.5 1.0

P.M.Collins, K.I.Hidari, H.Blanchard. Slow Diffusion of Lactose Out of Galectin-3 Crystals Monitored By X-Ray Crystallography: Possible Implications For Ligand-Exchange Protocols. Acta Crystallogr.,Sect.D V. 63 415 2007.
ISSN: ISSN 0907-4449
PubMed: 17327679
DOI: 10.1107/S090744490605270X