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Chlorine in PDB 2np0: Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain

Enzymatic activity of Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain

All present enzymatic activity of Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain:
3.4.24.69;

Protein crystallography data

The structure of Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain, PDB code: 2np0 was solved by Q.Chai, J.W.Arndt, R.C.Stevens, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 40.00 / 2.62
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 170.415, 351.971, 101.968, 90.00, 90.00, 90.00
R / Rfree (%) 18.6 / 22.7

Other elements in 2np0:

The structure of Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain also contains other interesting chemical elements:

Calcium (Ca) 3 atoms
Zinc (Zn) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain (pdb code 2np0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain, PDB code: 2np0:

Chlorine binding site 1 out of 1 in 2np0

Go back to Chlorine Binding Sites List in 2np0
Chlorine binding site 1 out of 1 in the Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Botulinum Neurotoxin Type B Complexed with Synaptotagamin-II Ectodomain within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1294

b:66.8
occ:1.00
NZ A:LYS1267 2.9 58.1 1.0
NZ A:LYS1210 3.0 45.3 1.0
O A:HOH1509 3.2 44.2 1.0
O A:HOH1536 3.2 37.4 1.0
CE A:LYS1267 3.4 57.6 1.0
CE1 A:TYR1212 3.6 43.1 1.0
CE A:LYS1210 3.8 47.5 1.0
CD1 A:TYR1212 4.0 42.2 1.0
CZ A:TYR1212 4.6 42.1 1.0
OH A:TYR1212 4.9 42.9 1.0
CD A:LYS1267 4.9 57.3 1.0
OE1 A:GLU1163 5.0 48.5 1.0

Reference:

Q.Chai, J.W.Arndt, M.Dong, W.H.Tepp, E.A.Johnson, E.R.Chapman, R.C.Stevens. Structural Basis of Cell Surface Receptor Recognition By Botulinum Neurotoxin B. Nature V. 444 1096 2006.
ISSN: ISSN 0028-0836
PubMed: 17167418
DOI: 10.1038/NATURE05411
Page generated: Sat Jul 20 09:11:27 2024

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