Chlorine in PDB 2nrt: Crystal Structure of the C-Terminal Half of Uvrc

The structure of Crystal Structure of the C-Terminal Half of Uvrc, PDB code: 2nrt was solved by E.Karakas, J.J.Truglio, C.Kisker, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 1.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	35.375, 72.782, 91.740, 90.00, 90.00, 90.00
R / Rfree (%)	18.5 / 22.1

The binding sites of Chlorine atom in the Crystal Structure of the C-Terminal Half of Uvrc (pdb code 2nrt). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Crystal Structure of the C-Terminal Half of Uvrc, PDB code: 2nrt:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in the Crystal Structure of the C-Terminal Half of Uvrc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the C-Terminal Half of Uvrc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:46.2 occ:1.00 O A:HOH204 2.7 46.9 1.0 O A:ARG478 2.8 21.4 1.0 CG A:GLN482 3.5 24.8 1.0 C A:ARG478 3.6 21.5 1.0 CG1 A:VAL481 3.7 21.9 1.0 CB A:VAL481 3.8 20.5 1.0 CA A:ARG478 3.8 23.2 1.0 N A:GLN482 3.8 20.0 1.0 CD A:ARG478 3.9 42.8 1.0 CB A:ARG478 4.0 25.3 1.0 NH1 A:ARG478 4.1 52.2 1.0 C A:VAL481 4.2 20.1 1.0 CA A:GLN482 4.3 20.8 1.0 CB A:GLN482 4.4 21.8 1.0 CA A:VAL481 4.5 20.0 1.0 CD A:GLN482 4.5 25.7 1.0 CG A:ARG478 4.6 32.8 1.0 NE A:ARG478 4.6 46.6 1.0 CZ A:ARG478 4.7 49.4 1.0 N A:LEU479 4.9 20.8 1.0 OE1 A:GLN482 4.9 31.5 1.0 CG2 A:VAL481 4.9 23.4 1.0 O A:VAL481 5.0 20.4 1.0

Chlorine binding site 2 out of 5 in the Crystal Structure of the C-Terminal Half of Uvrc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the C-Terminal Half of Uvrc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl302 b:45.9 occ:1.00 CE A:LYS520 3.0 37.0 1.0 NZ A:LYS520 3.2 37.9 1.0 CB A:PRO516 3.6 30.6 1.0 O A:HOH193 3.8 41.8 1.0 NH2 A:ARG505 4.3 56.5 1.0 CD A:LYS520 4.5 34.5 1.0 CA A:PRO516 4.6 30.5 1.0 CG A:PRO516 4.7 31.0 1.0 CG A:LYS520 5.0 31.0 1.0

Chlorine binding site 3 out of 5 in the Crystal Structure of the C-Terminal Half of Uvrc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the C-Terminal Half of Uvrc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl303 b:39.0 occ:1.00 NZ A:LYS419 3.0 39.4 1.0 O A:HOH201 3.0 48.2 1.0 O A:HOH182 3.1 31.8 1.0 NE A:ARG394 3.1 20.4 1.0 NE2 A:HIS420 3.2 31.2 1.0 CE1 A:HIS420 3.5 33.2 1.0 CE A:LYS419 3.8 37.5 1.0 NH2 A:ARG394 3.9 22.5 1.0 CD A:ARG394 3.9 19.2 1.0 CZ A:ARG394 4.0 19.9 1.0 CD A:LYS419 4.2 36.1 1.0 O A:HOH25 4.3 33.5 1.0 CD2 A:HIS420 4.5 29.4 1.0 CG A:ARG394 4.6 18.2 1.0 ND1 A:HIS420 4.8 32.0 1.0

Chlorine binding site 4 out of 5 in the Crystal Structure of the C-Terminal Half of Uvrc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the C-Terminal Half of Uvrc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl304 b:76.1 occ:1.00 CE2 A:TYR494 3.3 21.0 1.0 CZ A:TYR494 3.8 21.1 1.0 CD2 A:TYR494 3.9 22.2 1.0 OH A:TYR494 4.0 19.1 1.0 O A:TYR494 4.1 25.0 1.0 OH A:TYR375 4.5 26.1 1.0 O A:HOH141 4.6 73.7 1.0 CE1 A:TYR494 4.6 19.9 1.0 CG A:TYR494 4.7 20.0 1.0 ND1 A:HIS495 4.8 35.5 1.0 C A:TYR494 4.9 24.9 1.0

Chlorine binding site 5 out of 5 in the Crystal Structure of the C-Terminal Half of Uvrc


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of the C-Terminal Half of Uvrc within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl305 b:38.5 occ:1.00 O A:ASP392 2.7 18.1 1.0 O A:HOH91 2.8 44.2 1.0 NH2 A:ARG416 2.8 20.5 1.0 NH1 A:ARG416 3.1 20.2 1.0 CZ A:ARG416 3.4 20.2 1.0 CE1 A:HIS420 3.5 33.2 1.0 C A:ASP392 3.7 16.6 1.0 CG A:ARG394 3.7 18.2 1.0 ND1 A:HIS420 3.8 32.0 1.0 CB A:ASP392 3.9 18.3 1.0 CA A:ASP392 4.0 18.4 1.0 O A:HOH167 4.1 43.8 1.0 CZ A:ARG394 4.1 19.9 1.0 NE A:ARG394 4.2 20.4 1.0 NH2 A:ARG362 4.2 25.0 1.0 NE2 A:HIS420 4.3 31.2 1.0 NH2 A:ARG394 4.4 22.5 1.0 CG A:ASP392 4.4 22.3 1.0 NH1 A:ARG394 4.5 20.1 1.0 CD A:ARG394 4.6 19.2 1.0 NE A:ARG416 4.7 19.5 1.0 CG2 A:VAL382 4.7 17.3 1.0 CG A:HIS420 4.8 29.2 1.0 OD2 A:ASP392 4.8 26.6 1.0 CB A:ARG394 4.9 18.0 1.0 N A:TYR393 4.9 16.2 1.0 O A:HOH201 4.9 48.2 1.0 OD1 A:ASP392 4.9 27.5 1.0 CD2 A:LEU380 5.0 20.2 1.0

E.Karakas, J.J.Truglio, D.Croteau, B.Rhau, L.Wang, B.Van Houten, C.Kisker. Structure of the C-Terminal Half of Uvrc Reveals An Rnase H Endonuclease Domain with An Argonaute-Like Catalytic Triad. Embo J. V. 26 613 2007.
ISSN: ISSN 0261-4189
PubMed: 17245438
DOI: 10.1038/SJ.EMBOJ.7601497