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Atomistry » Chlorine » PDB 2o9s-2ol0 » 2oji » |
Chlorine in PDB 2oji: Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-CarboxamideEnzymatic activity of Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide
All present enzymatic activity of Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide:
2.7.11.24; Protein crystallography data
The structure of Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide, PDB code: 2oji
was solved by
X.Xie,
M.D.Jacobs,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide
(pdb code 2oji). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide, PDB code: 2oji: Chlorine binding site 1 out of 1 in 2ojiGo back to Chlorine Binding Sites List in 2oji
Chlorine binding site 1 out
of 1 in the Crystal Structure of ERK2 in Complex with N-Benzyl-4-(4-(3- Chlorophenyl)-1H-Pyrazol-3-Yl)-1H-Pyrrole-2-Carboxamide
Mono view Stereo pair view
Reference:
A.M.Aronov,
C.Baker,
G.W.Bemis,
J.Cao,
G.Chen,
P.J.Ford,
U.A.Germann,
J.Green,
M.R.Hale,
M.Jacobs,
J.W.Janetka,
F.Maltais,
G.Martinez-Botella,
M.N.Namchuk,
J.Straub,
Q.Tang,
X.Xie.
Flipped Out: Structure-Guided Design of Selective Pyrazolylpyrrole Erk Inhibitors. J.Med.Chem. V. 50 1280 2007.
Page generated: Sat Dec 12 09:13:20 2020
ISSN: ISSN 0022-2623 PubMed: 17300186 DOI: 10.1021/JM061381F |
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