Chlorine in PDB 2p0a: The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp

The structure of The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp, PDB code: 2p0a was solved by A.P.Turnbull, C.Phillips, A.C.W.Pike, J.M.Elkins, C.Gileadi, E.Salah, F.H.Niesen, N.Burgess, O.Gileadi, F.Gorrec, C.Umeano, F.Von Delft, J.Weigelt, A.Edwards, C.H.Arrowsmith, M.Sundstrom, D.Doyle, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.00 / 1.90
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	130.796, 73.186, 78.398, 90.00, 100.74, 90.00
R / Rfree (%)	18.1 / 21.8

The binding sites of Chlorine atom in the The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp (pdb code 2p0a). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp, PDB code: 2p0a:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl501 b:20.3 occ:1.00 O A:HOH745 3.0 21.3 1.0 N A:HIS253 3.3 23.6 1.0 CB A:SER170 3.4 28.1 1.0 N A:ALA172 3.5 27.3 1.0 C A:SER170 3.5 27.8 1.0 CA A:ALA252 3.5 23.9 1.0 CA A:SER170 3.6 27.8 1.0 CB A:ALA252 3.7 23.6 1.0 N A:MET171 3.7 27.6 1.0 CB A:ALA172 3.7 26.2 1.0 N A:LEU173 3.9 28.2 1.0 C A:ALA252 3.9 23.8 1.0 CG A:LEU173 3.9 28.4 1.0 O A:SER170 4.0 27.9 1.0 CA A:ALA172 4.0 27.1 1.0 CD2 A:HIS253 4.1 26.8 1.0 OG A:SER170 4.2 30.4 1.0 O A:HIS253 4.2 22.7 1.0 CA A:HIS253 4.2 24.3 1.0 CB A:HIS253 4.3 24.9 1.0 C A:ALA172 4.4 27.5 1.0 C A:MET171 4.5 27.5 1.0 CD1 A:LEU173 4.5 27.5 1.0 CG A:HIS253 4.5 24.6 1.0 CB A:LEU173 4.6 28.4 1.0 C A:HIS253 4.6 23.7 1.0 O A:HIS251 4.6 23.3 1.0 CA A:MET171 4.7 27.7 1.0 O A:HOH783 4.7 23.8 1.0 CB A:MET256 4.7 26.1 1.0 CD2 A:LEU173 4.8 29.9 1.0 N A:ALA252 4.8 23.9 1.0 CA A:LEU173 4.8 27.8 1.0 O A:HOH774 4.9 26.4 1.0 CG A:MET256 5.0 27.4 1.0

Chlorine binding site 2 out of 2 in the The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl501 b:23.2 occ:1.00 O B:HOH740 3.0 19.8 1.0 N B:HIS253 3.3 23.9 1.0 N B:ALA172 3.3 26.2 1.0 CB B:SER170 3.5 27.2 1.0 CB B:ALA172 3.6 26.9 1.0 CA B:ALA252 3.6 23.8 1.0 C B:SER170 3.6 26.5 1.0 N B:LEU173 3.7 27.4 1.0 CB B:ALA252 3.7 24.1 1.0 CA B:SER170 3.7 26.4 1.0 N B:MET171 3.8 26.4 1.0 CA B:ALA172 3.8 26.6 1.0 CG B:LEU173 3.9 29.1 1.0 C B:ALA252 3.9 24.0 1.0 O B:SER170 4.0 26.0 1.0 C B:ALA172 4.2 26.8 1.0 O B:HIS253 4.2 23.3 1.0 CA B:HIS253 4.3 24.1 1.0 CD2 B:HIS253 4.3 24.3 1.0 OG B:SER170 4.3 30.1 1.0 C B:MET171 4.4 26.4 1.0 CD1 B:LEU173 4.4 29.3 1.0 CB B:HIS253 4.4 24.1 1.0 CB B:LEU173 4.4 28.0 1.0 O B:HOH821 4.5 27.8 1.0 CB B:MET256 4.6 26.3 1.0 C B:HIS253 4.6 23.4 1.0 CG B:HIS253 4.7 24.0 1.0 CA B:MET171 4.7 26.7 1.0 CA B:LEU173 4.7 27.8 1.0 CG B:MET256 4.7 28.3 1.0 O B:HOH789 4.8 26.3 1.0 O B:HIS251 4.8 23.2 1.0 CD2 B:LEU173 4.8 28.5 1.0 N B:ALA252 4.9 23.9 1.0

A.P.Turnbull, C.Phillips, A.C.W.Pike, J.M.Elkins, C.Gileadi, E.Salah, F.H.Niesen, N.Burgess, O.Gileadi, F.Gorrec, C.Umeano, F.Von Delft, J.Weigelt, A.Edwards, C.H.Arrowsmith, M.Sundstrom, D.Doyle. The Crystal Structure of Human Synapsin III (SYN3) in Complex with Amppnp To Be Published.