Chlorine in PDB 2p0e: Human Nicotinamide Riboside Kinase 1 in Complex with Tiazofurin

The structure of Human Nicotinamide Riboside Kinase 1 in Complex with Tiazofurin, PDB code: 2p0e was solved by W.M.Rabeh, W.Tempel, L.Nedyalkova, R.Landry, C.H.Arrowsmith, A.M.Edwards, M.Sundstrom, J.Weigelt, A.Bochkarev, C.Brenner, H.Park, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.84 / 1.80
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	55.608, 141.571, 62.005, 90.00, 90.00, 90.00
R / Rfree (%)	17.5 / 20.9

The binding sites of Chlorine atom in the Human Nicotinamide Riboside Kinase 1 in Complex with Tiazofurin (pdb code 2p0e). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Nicotinamide Riboside Kinase 1 in Complex with Tiazofurin, PDB code: 2p0e:

Chlorine binding site 1 out of 1 in the Human Nicotinamide Riboside Kinase 1 in Complex with Tiazofurin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Nicotinamide Riboside Kinase 1 in Complex with Tiazofurin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl251 b:34.9 occ:1.00 N A:SER82 3.2 23.8 1.0 CB A:SER82 3.4 34.5 1.0 O A:HOH431 3.8 25.9 1.0 CA A:SER82 3.9 32.0 1.0 CG2 A:VAL81 4.0 20.4 1.0 C A:VAL81 4.1 21.9 1.0 CA A:VAL81 4.2 18.8 1.0 O A:HOH430 4.6 29.1 1.0 OG A:SER82 4.6 38.2 1.0 CB A:VAL81 4.8 19.6 1.0 O A:SER82 4.9 35.8 1.0 C A:SER82 4.9 36.1 1.0

W.Tempel, W.M.Rabeh, K.L.Bogan, P.Belenky, M.Wojcik, H.F.Seidle, L.Nedyalkova, T.Yang, A.A.Sauve, H.W.Park, C.Brenner. Nicotinamide Riboside Kinase Structures Reveal New Pathways to Nad(+). Plos Biol. V. 5 E263 2007.
ISSN: ISSN 1544-9173
PubMed: 17914902
DOI: 10.1371/JOURNAL.PBIO.0050263