Chlorine in PDB 2p0w: Human Histone Acetyltransferase 1 (HAT1)

All present enzymatic activity of Human Histone Acetyltransferase 1 (HAT1):
2.3.1.48;

The structure of Human Histone Acetyltransferase 1 (HAT1), PDB code: 2p0w was solved by H.Wu, J.Min, H.Zeng, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov, Structural Genomics Consortium(Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.35 / 1.90
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	116.557, 155.425, 53.617, 90.00, 90.00, 90.00
R / Rfree (%)	18.2 / 22.8

The binding sites of Chlorine atom in the Human Histone Acetyltransferase 1 (HAT1) (pdb code 2p0w). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Histone Acetyltransferase 1 (HAT1), PDB code: 2p0w:

Chlorine binding site 1 out of 1 in the Human Histone Acetyltransferase 1 (HAT1)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Histone Acetyltransferase 1 (HAT1) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl806 b:32.0 occ:1.00 O A:HOH1170 1.9 35.1 1.0 O A:HOH1023 2.5 37.1 1.0 NH1 A:ARG286 3.4 18.9 1.0 N A:ALA275 3.5 12.0 1.0 O A:ALA275 3.6 13.7 1.0 NE2 A:HIS327 3.7 15.7 1.0 NH2 A:ARG286 4.0 20.5 1.0 CE1 A:HIS327 4.1 14.7 1.0 CZ A:ARG286 4.2 23.6 1.0 CB A:THR274 4.2 12.9 1.0 CA A:ALA275 4.2 12.3 1.0 CB A:ALA275 4.3 11.9 1.0 C A:ALA275 4.3 13.2 1.0 CG A:PRO278 4.3 22.2 1.0 C A:THR274 4.4 12.3 1.0 CA A:THR274 4.4 12.5 1.0 CD A:PRO278 4.4 22.3 1.0 O A:HOH887 4.6 22.1 1.0 O A:HOH1072 4.7 35.5 1.0 OE1 A:GLN326 4.8 30.7 1.0 CD2 A:HIS327 4.9 15.4 1.0 CG2 A:THR274 5.0 14.5 1.0

H.Wu, J.Min, H.Zeng, P.Loppnau, J.Weigelt, M.Sundstrom, C.H.Arrowsmith, A.M.Edwards, A.Bochkarev, A.N.Plotnikov. The Crystal Structure of Human Histone Acetyltransferase 1 (HAT1) in Complex with Acetylcoenzyme A and Histone Peptide H4 To Be Published.