Chlorine in PDB 2p31: Crystal Structure of Human Glutathione Peroxidase 7

All present enzymatic activity of Crystal Structure of Human Glutathione Peroxidase 7:
1.11.1.9;

The structure of Crystal Structure of Human Glutathione Peroxidase 7, PDB code: 2p31 was solved by K.L.Kavanagh, C.Johansson, E.Papagrigoriou, G.Kochan, C.Umeano, O.Gileadi, F.Von Delft, J.Weigelt, C.H.Arrowsmith, M.Sundstrom, A.Edwards, U.Oppermann, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	32.046, 56.224, 94.593, 90.00, 91.27, 90.00
R / Rfree (%)	16.3 / 21.5

The binding sites of Chlorine atom in the Crystal Structure of Human Glutathione Peroxidase 7 (pdb code 2p31). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Glutathione Peroxidase 7, PDB code: 2p31:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human Glutathione Peroxidase 7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Glutathione Peroxidase 7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl202 b:27.9 occ:1.00 OG1 A:THR173 3.2 16.9 0.5 OG1 A:THR173 3.3 18.6 0.5 CG2 A:THR173 3.5 16.2 0.5 NE A:ARG169 3.7 20.9 1.0 CB A:THR173 3.8 14.5 0.5 CA A:PRO170 3.8 18.8 1.0 CB A:THR173 3.9 15.9 0.5 CG2 A:THR173 4.0 11.6 0.5 CG A:PRO170 4.1 16.8 1.0 CB A:PRO170 4.2 17.0 1.0 N A:PRO170 4.3 17.6 1.0 NH2 A:ARG169 4.3 23.0 1.0 O A:HOH224 4.3 19.2 1.0 CG A:ARG169 4.5 16.2 1.0 CZ A:ARG169 4.5 14.7 1.0 CD A:ARG169 4.5 18.5 1.0 CD A:PRO170 4.7 19.9 1.0 C A:ARG169 4.7 15.8 1.0 O A:ARG169 4.7 16.2 1.0 C A:PRO170 5.0 18.3 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human Glutathione Peroxidase 7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Glutathione Peroxidase 7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl201 b:27.0 occ:1.00 OG1 B:THR173 3.2 14.0 0.5 CG2 B:THR173 3.4 14.8 0.5 OG1 B:THR173 3.4 22.3 0.5 NE B:ARG169 3.7 21.5 1.0 CA B:PRO170 3.8 16.7 1.0 CB B:THR173 3.9 15.6 0.5 CB B:THR173 3.9 17.5 0.5 CB B:PRO170 4.1 16.0 1.0 CG2 B:THR173 4.1 14.4 0.5 CG B:PRO170 4.1 14.6 1.0 NH2 B:ARG169 4.2 23.4 1.0 N B:PRO170 4.2 17.3 1.0 O B:HOH233 4.3 17.6 1.0 CG B:ARG169 4.4 18.8 1.0 CZ B:ARG169 4.4 22.6 1.0 CD B:ARG169 4.5 17.5 1.0 CD B:PRO170 4.6 16.2 1.0 O B:ARG169 4.6 15.2 1.0 C B:ARG169 4.6 14.6 1.0

K.L.Kavanagh, U.Oppermann. Crystal Structure of Human Glutathione Peroxidase 7 To Be Published.