Chlorine in PDB 2p67: Crystal Structure of Lao/Ao Transport System Kinase

The structure of Crystal Structure of Lao/Ao Transport System Kinase, PDB code: 2p67 was solved by U.A.Ramagopal, J.Adams, L.Rodgers, R.Toro, K.Bain, M.Rutter, K.Schwinn, J.M.Sauder, S.K.Burley, S.C.Almo, New York Sgx Research Center Forstructural Genomics (Nysgxrc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.19 / 1.80
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	56.311, 108.452, 141.296, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 23

The structure of Crystal Structure of Lao/Ao Transport System Kinase also contains other interesting chemical elements:

Sodium

(Na)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Lao/Ao Transport System Kinase (pdb code 2p67). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of Lao/Ao Transport System Kinase, PDB code: 2p67:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of Lao/Ao Transport System Kinase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Lao/Ao Transport System Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:21.8 occ:0.70 NE2 A:HIS36 3.2 32.6 1.0 CE1 A:HIS36 3.8 34.2 1.0 CD2 A:HIS36 4.3 33.3 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of Lao/Ao Transport System Kinase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Lao/Ao Transport System Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:38.6 occ:0.70 O A:HOH599 2.9 42.5 1.0 CG2 A:THR261 3.4 27.5 1.0 N A:GLN267 3.4 25.3 1.0 CB A:LEU266 3.4 24.6 1.0 CA A:THR261 3.5 26.7 1.0 CB A:THR261 3.6 26.3 1.0 OE1 A:GLN267 3.6 35.0 1.0 CG A:GLN267 3.7 31.0 1.0 N A:LEU266 3.8 23.6 1.0 CA A:LEU266 3.9 24.3 1.0 CD A:GLN267 3.9 36.8 1.0 CA A:GLY264 4.1 24.2 1.0 C A:LEU266 4.1 24.5 1.0 O A:THR261 4.1 28.2 1.0 CB A:GLN267 4.1 27.1 1.0 C A:GLY264 4.2 24.1 1.0 CA A:GLN267 4.3 26.2 1.0 C A:THR261 4.3 27.3 1.0 O A:LEU260 4.4 25.1 1.0 N A:THR261 4.4 24.4 1.0 O A:GLY264 4.5 23.8 1.0 CG A:LEU266 4.5 26.0 1.0 N A:ARG265 4.6 23.1 1.0 C A:LEU260 4.8 24.6 1.0 N A:GLY264 4.8 24.9 1.0 O A:HOH486 4.8 36.2 1.0 CD2 A:LEU266 4.8 26.5 1.0 C A:ARG265 4.9 22.9 1.0 O A:HOH613 4.9 42.9 1.0 OG1 A:THR261 5.0 27.3 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of Lao/Ao Transport System Kinase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of Lao/Ao Transport System Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl404 b:45.4 occ:1.00 NE2 A:GLN320 3.2 37.1 1.0 CB A:ALA306 4.0 24.4 1.0 CD1 A:LEU312 4.1 34.0 1.0 CD A:GLN320 4.2 37.6 1.0 O A:GLN302 4.2 27.4 1.0 OE1 A:GLN320 4.3 36.8 1.0 O A:HOH501 4.4 36.8 1.0 CA A:THR303 4.4 27.3 1.0 OG1 A:THR303 4.5 27.1 1.0 C A:GLN302 4.5 28.6 1.0 N A:THR303 4.6 27.6 1.0 CG A:LEU312 4.9 30.7 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of Lao/Ao Transport System Kinase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of Lao/Ao Transport System Kinase within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl405 b:30.4 occ:1.00 N A:ARG226 3.2 19.9 1.0 O A:HOH611 3.2 34.2 1.0 O A:HOH459 3.5 29.3 1.0 CA A:ARG225 3.7 19.9 1.0 CG A:ARG226 3.7 21.1 1.0 CG A:ARG225 3.9 24.9 1.0 C A:ARG225 3.9 20.4 1.0 CB A:ARG226 4.0 20.5 1.0 CA A:ARG226 4.2 19.9 1.0 CD A:ARG226 4.2 24.8 1.0 CB A:ARG225 4.4 20.4 1.0 O A:LEU224 4.7 18.3 1.0 O A:HOH457 4.7 31.3 1.0 NE A:ARG226 4.7 28.3 1.0 N A:ARG225 4.8 19.2 1.0

U.A.Ramagopal, J.Adams, L.Rodgers, R.Toro, K.Bain, M.Rutter, K.Schwinn, J.M.Sauder, S.K.Burley, S.C.Almo. Crystal Structure of Lao/Ao Transport System Kinase To Be Published.