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Atomistry » Chlorine » PDB 2pg4-2pwr » 2phb » |
Chlorine in PDB 2phb: An Orally Efficacious Factor Xa InhibitorEnzymatic activity of An Orally Efficacious Factor Xa Inhibitor
All present enzymatic activity of An Orally Efficacious Factor Xa Inhibitor:
3.4.21.6; Protein crystallography data
The structure of An Orally Efficacious Factor Xa Inhibitor, PDB code: 2phb
was solved by
E.Zhang,
J.T.Kohrt,
C.F.Bigge,
B.C.Finzel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2phb:
The structure of An Orally Efficacious Factor Xa Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the An Orally Efficacious Factor Xa Inhibitor
(pdb code 2phb). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the An Orally Efficacious Factor Xa Inhibitor, PDB code: 2phb: Chlorine binding site 1 out of 1 in 2phbGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the An Orally Efficacious Factor Xa Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
J.T.Kohrt,
C.F.Bigge,
J.W.Bryant,
A.Casimiro-Garcia,
L.Chi,
W.L.Cody,
T.Dahring,
D.A.Dudley,
K.J.Filipski,
S.Haarer,
R.Heemstra,
N.Janiczek,
L.Narasimhan,
T.Mcclanahan,
J.T.Peterson,
V.Sahasrabudhe,
R.Schaum,
C.A.Van Huis,
K.M.Welch,
E.Zhang,
R.J.Leadley,
J.J.Edmunds.
The Discovery of (2R,4R)-N-(4-Chlorophenyl)-N- (2-Fluoro-4-(2-Oxopyridin-1(2H)-Yl)Phenyl) -4-Methoxypyrrolidine-1,2-Dicarboxamide (Pd 0348292), An Orally Efficacious Factor Xa Inhibitor Chem.Biol.Drug Des. V. 70 100 2007.
Page generated: Sat Dec 12 09:15:22 2020
ISSN: ISSN 1747-0277 PubMed: 17683371 DOI: 10.1111/J.1747-0285.2007.00539.X |
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