Chlorine in PDB 2q0g: Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu

All present enzymatic activity of Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu:
2.7.7.52;

The structure of Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu, PDB code: 2q0g was solved by J.Stagno, H.Luecke, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.52 / 2.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	81.544, 41.953, 106.593, 90.00, 95.62, 90.00
R / Rfree (%)	22.8 / 29.6

The structure of Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Chlorine atom in the Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu (pdb code 2q0g). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu, PDB code: 2q0g:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl403 b:48.1 occ:1.00 ND1 A:HIS246 2.2 37.7 1.0 O A:HOH523 2.3 27.1 1.0 ND1 A:HIS250 2.3 41.7 1.0 O A:HOH610 2.9 50.6 1.0 CE1 A:HIS250 3.0 42.8 1.0 CE1 A:HIS246 3.2 40.0 1.0 CG A:HIS246 3.2 35.9 1.0 CG A:HIS250 3.4 39.5 1.0 CB A:HIS246 3.5 33.6 1.0 CA A:HIS246 3.8 33.0 1.0 CB A:HIS250 4.0 38.0 1.0 NE2 A:HIS250 4.1 43.3 1.0 O A:HIS246 4.2 33.2 1.0 NE2 A:HIS246 4.3 39.1 1.0 CD2 A:HIS246 4.4 38.5 1.0 CD2 A:HIS250 4.4 41.5 1.0 C A:HIS246 4.4 32.9 1.0 O A:HOH587 4.6 47.8 1.0 NH1 A:ARG325 4.7 55.9 1.0

Chlorine binding site 2 out of 2 in the Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Terminal Uridylyl Transferase 4 From Trypanosoma Brucei with Bound Upu within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl404 b:28.1 occ:1.00 O B:HOH504 2.3 17.8 1.0 O B:HOH552 2.3 38.8 1.0 ND1 B:HIS246 2.4 32.8 1.0 ND1 B:HIS250 2.4 33.9 1.0 CE1 B:HIS250 3.1 34.3 1.0 CE1 B:HIS246 3.3 29.2 1.0 CG B:HIS246 3.4 33.1 1.0 CG B:HIS250 3.6 36.0 1.0 CB B:HIS246 3.7 32.2 1.0 CA B:HIS246 3.9 32.3 1.0 CB B:HIS250 4.1 37.2 1.0 NE2 B:HIS250 4.3 34.7 1.0 O B:HIS246 4.3 33.0 1.0 NE2 B:HIS246 4.4 30.6 1.0 CD2 B:HIS246 4.5 30.5 1.0 CD2 B:HIS250 4.6 35.4 1.0 C B:HIS246 4.6 32.1 1.0 NE B:ARG325 5.0 59.4 1.0

J.Stagno, I.Aphasizheva, R.Aphasizhev, H.Luecke. Dual Role of the Rna Substrate in Selectivity and Catalysis By Terminal Uridylyl Transferases. Proc.Natl.Acad.Sci.Usa V. 104 14634 2007.
ISSN: ISSN 0027-8424
PubMed: 17785418
DOI: 10.1073/PNAS.0704259104