Chlorine »
PDB 2q6r-2qhf »
2qc8 »
Chlorine in PDB 2qc8: Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Enzymatic activity of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
All present enzymatic activity of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate:
6.3.1.2;
6.3.1.2;
Protein crystallography data
The structure of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate, PDB code: 2qc8
was solved by
T.Karlberg,
L.Lehtio,
C.H.Arrowsmith,
H.Berglund,
R.D.Busam,
R.Collins,
L.G.Dahlgren,
A.Edwards,
S.Flodin,
A.Flores,
S.Graslund,
M.Hammarstrom,
M.Hogbom,
I.Johansson,
A.Kallas,
T.Kotenyova,
M.Moche,
P.Nordlund,
T.Nyman,
C.Persson,
J.Sagemark,
M.Sundstrom,
A.G.Thorsell,
S.Van Denberg,
J.Weigelt,
L.Holmberg-Schiavone,
Structural Genomics Consortium(Sgc),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 39.94 / 2.60 |
| Space group | C 1 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 181.210, 126.080, 188.170, 90.00, 92.14, 90.00 |
| R / Rfree (%) | 16.6 / 21.7 |
Other elements in 2qc8:
The structure of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate also contains other interesting chemical elements:
| Manganese | (Mn) | 30 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
(pdb code 2qc8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 10 binding sites of Chlorine where determined in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate, PDB code: 2qc8:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;
In total 10 binding sites of Chlorine where determined in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate, PDB code: 2qc8:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;
Chlorine binding site 1 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 1 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 2 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 2 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 3 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 3 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 3 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 4 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 4 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 4 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 5 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 5 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 5 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 6 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 6 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 6 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 7 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 7 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 7 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 8 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 8 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 8 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 9 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 9 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 9 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Chlorine binding site 10 out of 10 in 2qc8
Go back to
Chlorine Binding Sites List in 2qc8
Chlorine binding site 10 out
of 10 in the Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 10 of Crystal Structure of Human Glutamine Synthetase in Complex with Adp and Methionine Sulfoximine Phosphate within 5.0Å range:
|
Reference:
W.W.Krajewski,
R.Collins,
L.Holmberg-Schiavone,
T.A.Jones,
T.Karlberg,
S.L.Mowbray.
Crystal Structures of Mammalian Glutamine Synthetases Illustrate Substrate-Induced Conformational Changes and Provide Opportunities For Drug and Herbicide Design. J.Mol.Biol. V. 375 217 2008.
ISSN: ISSN 0022-2836
PubMed: 18005987
DOI: 10.1016/J.JMB.2007.10.029
Page generated: Sat Jul 20 10:34:46 2024
ISSN: ISSN 0022-2836
PubMed: 18005987
DOI: 10.1016/J.JMB.2007.10.029
Last articles
Zn in 9JPJZn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
