Atomistry » Chlorine » PDB 2qih-2qu3 » 2qts
Atomistry »
  Chlorine »
    PDB 2qih-2qu3 »
      2qts »

Chlorine in PDB 2qts: Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH

Protein crystallography data

The structure of Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH, PDB code: 2qts was solved by J.Jasti, H.Furukawa, E.B.Gonzales, E.Gouaux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.90
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 124.252, 110.781, 149.891, 90.00, 97.54, 90.00
R / Rfree (%) 20.8 / 23.3

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH (pdb code 2qts). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 6 binding sites of Chlorine where determined in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH, PDB code: 2qts:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6;

Chlorine binding site 1 out of 6 in 2qts

Go back to Chlorine Binding Sites List in 2qts
Chlorine binding site 1 out of 6 in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl464

b:26.9
occ:1.00
 OE2 A:GLU314 3.1 22.2 1.0
NZ C:LYS212 3.3 23.5 1.0
NE A:ARG310 3.3 18.9 1.0
NH1 A:ARG310 3.4 18.2 1.0
CG A:GLU314 3.7 20.9 1.0
CZ A:ARG310 3.8 19.5 1.0
CD A:GLU314 3.8 23.8 1.0
CD C:LYS212 3.9 22.2 1.0
O A:LEU352 3.9 19.7 1.0
CB A:CYS360 4.0 35.0 1.0
CE C:LYS212 4.1 24.2 1.0
CB A:LEU352 4.1 21.0 1.0
C A:LEU352 4.2 19.2 1.0
CB A:ARG310 4.3 21.0 1.0
CG A:ARG310 4.4 22.8 1.0
CD A:ARG310 4.4 20.1 1.0
O A:CYS360 4.4 37.7 1.0
CG1 A:VAL353 4.5 16.7 1.0
N A:VAL353 4.6 19.6 1.0
O A:ARG310 4.7 22.1 1.0
CA A:VAL353 4.8 17.1 1.0
CA A:LEU352 4.8 19.6 1.0
CA A:ARG310 4.8 22.3 1.0
SG A:CYS360 4.9 36.9 1.0
CD1 A:LEU352 5.0 22.1 1.0

Chlorine binding site 2 out of 6 in 2qts

Go back to Chlorine Binding Sites List in 2qts
Chlorine binding site 2 out of 6 in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl464

b:29.4
occ:1.00
 OE2 B:GLU314 3.0 29.8 1.0
NE B:ARG310 3.3 24.5 1.0
NZ A:LYS212 3.3 22.4 1.0
NH1 B:ARG310 3.4 22.4 1.0
CG B:GLU314 3.7 28.4 1.0
CZ B:ARG310 3.8 24.8 1.0
CD B:GLU314 3.8 30.6 1.0
CD A:LYS212 3.9 24.0 1.0
O B:LEU352 4.0 23.9 1.0
CE A:LYS212 4.1 24.1 1.0
CB B:CYS360 4.2 48.1 1.0
CB B:LEU352 4.2 23.9 1.0
C B:LEU352 4.3 22.8 1.0
CB B:ARG310 4.3 25.6 1.0
CG1 B:VAL353 4.4 20.6 1.0
CD B:ARG310 4.4 24.8 1.0
CG B:ARG310 4.4 27.3 1.0
N B:VAL353 4.6 21.9 1.0
O B:ARG310 4.7 25.9 1.0
CA B:VAL353 4.7 21.8 1.0
SG B:CYS360 4.8 52.1 1.0
CA B:ARG310 4.8 26.5 1.0
CA B:LEU352 4.8 22.9 1.0
O B:CYS360 5.0 48.3 1.0

Chlorine binding site 3 out of 6 in 2qts

Go back to Chlorine Binding Sites List in 2qts
Chlorine binding site 3 out of 6 in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl464

b:24.2
occ:1.00
 OE2 C:GLU314 3.0 21.9 1.0
NZ B:LYS212 3.3 18.8 1.0
NE C:ARG310 3.3 18.0 1.0
NH1 C:ARG310 3.4 17.5 1.0
CG C:GLU314 3.7 20.8 1.0
CZ C:ARG310 3.8 18.2 1.0
CD C:GLU314 3.8 23.8 1.0
O C:LEU352 3.9 18.1 1.0
CD B:LYS212 4.0 19.8 1.0
CB C:CYS360 4.1 34.9 1.0
CB C:LEU352 4.1 19.4 1.0
C C:LEU352 4.2 17.3 1.0
CE B:LYS212 4.2 18.5 1.0
CB C:ARG310 4.3 17.0 1.0
CG1 C:VAL353 4.4 15.8 1.0
CD C:ARG310 4.4 18.8 1.0
CG C:ARG310 4.4 17.5 1.0
N C:VAL353 4.6 17.2 1.0
O C:CYS360 4.6 38.0 1.0
O C:ARG310 4.6 19.6 1.0
CA C:VAL353 4.7 16.6 1.0
CA C:LEU352 4.8 17.4 1.0
CA C:ARG310 4.8 20.7 1.0
SG C:CYS360 4.9 37.4 1.0

Chlorine binding site 4 out of 6 in 2qts

Go back to Chlorine Binding Sites List in 2qts
Chlorine binding site 4 out of 6 in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl4

b:31.2
occ:1.00
 OE2 D:GLU314 3.0 25.4 1.0
NE D:ARG310 3.2 22.8 1.0
NH1 D:ARG310 3.3 19.3 1.0
NZ F:LYS212 3.4 23.0 1.0
CG D:GLU314 3.7 25.0 1.0
CZ D:ARG310 3.7 22.4 1.0
CD D:GLU314 3.8 27.4 1.0
O D:LEU352 3.9 19.9 1.0
CD F:LYS212 4.0 23.6 1.0
CB D:CYS360 4.1 44.7 1.0
CB D:LEU352 4.1 20.6 1.0
CE F:LYS212 4.2 23.0 1.0
C D:LEU352 4.2 19.4 1.0
CB D:ARG310 4.4 23.0 1.0
CG1 D:VAL353 4.4 20.8 1.0
CD D:ARG310 4.4 23.9 1.0
CG D:ARG310 4.4 25.7 1.0
O D:ARG310 4.6 25.9 1.0
SG D:CYS360 4.6 47.9 1.0
N D:VAL353 4.6 19.7 1.0
CA D:VAL353 4.8 18.6 1.0
CA D:LEU352 4.8 20.0 1.0
CA D:ARG310 4.9 25.7 1.0
O D:CYS360 4.9 47.2 1.0

Chlorine binding site 5 out of 6 in 2qts

Go back to Chlorine Binding Sites List in 2qts
Chlorine binding site 5 out of 6 in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Cl5

b:31.7
occ:1.00
 OE2 E:GLU314 3.0 27.7 1.0
NH1 E:ARG310 3.3 19.5 1.0
NE E:ARG310 3.4 22.4 1.0
NZ D:LYS212 3.4 28.3 1.0
CG E:GLU314 3.7 25.2 1.0
CD E:GLU314 3.8 25.9 1.0
CZ E:ARG310 3.8 24.7 1.0
CD D:LYS212 4.0 28.4 1.0
O E:LEU352 4.0 23.1 1.0
CB E:CYS360 4.2 50.6 1.0
CB E:LEU352 4.2 24.7 1.0
C E:LEU352 4.2 23.7 1.0
CE D:LYS212 4.3 28.9 1.0
CB E:ARG310 4.4 23.6 1.0
CD E:ARG310 4.5 23.2 1.0
CG E:ARG310 4.6 24.2 1.0
CG1 E:VAL353 4.6 21.1 1.0
N E:VAL353 4.6 22.9 1.0
O E:ARG310 4.7 24.2 1.0
CA E:VAL353 4.7 21.4 1.0
SG E:CYS360 4.7 53.3 1.0
CA E:LEU352 4.8 22.9 1.0
CA E:ARG310 4.9 24.8 1.0
O E:CYS360 5.0 52.8 1.0
OE1 E:GLU314 5.0 25.9 1.0

Chlorine binding site 6 out of 6 in 2qts

Go back to Chlorine Binding Sites List in 2qts
Chlorine binding site 6 out of 6 in the Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Structure of An Acid-Sensing Ion Channel 1 at 1.9 A Resolution and Low pH within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Cl6

b:28.9
occ:1.00
 OE2 F:GLU314 3.1 26.3 1.0
NE F:ARG310 3.3 22.3 1.0
NZ E:LYS212 3.3 24.6 1.0
NH1 F:ARG310 3.4 21.4 1.0
CG F:GLU314 3.7 25.5 1.0
CD F:GLU314 3.8 27.5 1.0
CZ F:ARG310 3.8 21.3 1.0
O F:LEU352 3.9 21.1 1.0
CD E:LYS212 3.9 22.7 1.0
CB F:LEU352 4.1 23.8 1.0
CB F:CYS360 4.1 38.5 1.0
CE E:LYS212 4.1 22.4 1.0
C F:LEU352 4.2 22.8 1.0
CB F:ARG310 4.2 24.0 1.0
CG F:ARG310 4.4 23.6 1.0
CD F:ARG310 4.4 22.5 1.0
CG1 F:VAL353 4.4 20.8 1.0
O F:CYS360 4.4 41.0 1.0
N F:VAL353 4.6 21.5 1.0
O F:ARG310 4.6 22.2 1.0
CA F:VAL353 4.7 20.4 1.0
CA F:LEU352 4.7 22.7 1.0
CA F:ARG310 4.8 23.6 1.0
SG F:CYS360 5.0 39.5 1.0

Reference:

J.Jasti, H.Furukawa, E.B.Gonzales, E.Gouaux. Structure of Acid-Sensing Ion Channel 1 at 1.9A Resolution and Low pH Nature V. 449 316 2007.
ISSN: ISSN 0028-0836
PubMed: 17882215
DOI: 10.1038/NATURE06163
Page generated: Sat Jul 20 10:55:34 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy