Chlorine in PDB 2rg8: Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain

The structure of Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain, PDB code: 2rg8 was solved by R.Garces, C.Suzuki, G.Wagner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.68 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	37.680, 70.060, 110.880, 90.00, 90.00, 90.00
R / Rfree (%)	20.2 / 25.1

The structure of Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain also contains other interesting chemical elements:

Sodium

(Na)

3 atoms

The binding sites of Chlorine atom in the Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain (pdb code 2rg8). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain, PDB code: 2rg8:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1 b:15.0 occ:1.00 NZ A:LYS297 3.2 17.0 1.0 CE A:LYS297 3.9 18.1 1.0 CG1 A:VAL300 4.0 16.5 1.0 CD A:LYS297 4.3 15.8 1.0 CB A:VAL300 4.4 15.4 1.0 CG2 A:VAL300 4.5 14.0 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Programmed For Cell Death 4 Middle MA3 Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl2 b:24.1 occ:1.00 NH1 B:ARG292 3.2 19.7 1.0 N B:GLY284 3.3 17.8 1.0 N B:VAL286 3.4 14.9 1.0 O B:HOH511 3.5 43.5 1.0 N B:THR285 3.6 17.4 1.0 CB B:VAL286 3.7 14.0 1.0 CA B:GLY284 3.8 17.8 1.0 O B:VAL286 3.8 18.4 1.0 O B:TYR282 3.9 13.1 1.0 CD B:ARG292 3.9 16.4 1.0 CA B:VAL286 3.9 15.4 1.0 C B:GLY284 4.1 18.3 1.0 CG2 B:VAL286 4.1 13.6 1.0 C B:LYS283 4.3 16.6 1.0 CZ B:ARG292 4.3 19.6 1.0 C B:VAL286 4.3 17.0 1.0 C B:THR285 4.5 15.7 1.0 CA B:LYS283 4.5 16.4 1.0 NE B:ARG292 4.5 19.8 1.0 CA B:THR285 4.6 16.0 1.0 C B:TYR282 4.8 13.2 1.0 CG1 B:VAL286 4.9 14.6 1.0

C.Suzuki, R.G.Garces, K.A.Edmonds, S.Hiller, S.G.Hyberts, A.Marintchev, G.Wagner. PDCD4 Inhibits Translation Initiation By Binding to EIF4A Using Both Its MA3 Domains. Proc.Natl.Acad.Sci.Usa V. 105 3274 2008.
ISSN: ISSN 0027-8424
PubMed: 18296639
DOI: 10.1073/PNAS.0712235105