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Atomistry » Chlorine » PDB 2rh8-2uxg » 2uw9 » |
Chlorine in PDB 2uw9: Structure of Pkb-Beta (AKT2) Complexed with 4-(4-Chloro- Phenyl)-4-(4-(1H-Pyrazol-4-Yl)-Phenyl)-PiperidineEnzymatic activity of Structure of Pkb-Beta (AKT2) Complexed with 4-(4-Chloro- Phenyl)-4-(4-(1H-Pyrazol-4-Yl)-Phenyl)-Piperidine
All present enzymatic activity of Structure of Pkb-Beta (AKT2) Complexed with 4-(4-Chloro- Phenyl)-4-(4-(1H-Pyrazol-4-Yl)-Phenyl)-Piperidine:
2.7.11.1; 2.7.11.26; Protein crystallography data
The structure of Structure of Pkb-Beta (AKT2) Complexed with 4-(4-Chloro- Phenyl)-4-(4-(1H-Pyrazol-4-Yl)-Phenyl)-Piperidine, PDB code: 2uw9
was solved by
T.G.Davies,
G.Saxty,
S.J.Woodhead,
V.Berdini,
M.L.Verdonk,
P.G.Wyatt,
R.G.Boyle,
D.Barford,
R.Downham,
M.D.Garrett,
R.A.Carr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Pkb-Beta (AKT2) Complexed with 4-(4-Chloro- Phenyl)-4-(4-(1H-Pyrazol-4-Yl)-Phenyl)-Piperidine
(pdb code 2uw9). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Pkb-Beta (AKT2) Complexed with 4-(4-Chloro- Phenyl)-4-(4-(1H-Pyrazol-4-Yl)-Phenyl)-Piperidine, PDB code: 2uw9: Chlorine binding site 1 out of 1 in 2uw9Go back to Chlorine Binding Sites List in 2uw9
Chlorine binding site 1 out
of 1 in the Structure of Pkb-Beta (AKT2) Complexed with 4-(4-Chloro- Phenyl)-4-(4-(1H-Pyrazol-4-Yl)-Phenyl)-Piperidine
Mono view Stereo pair view
Reference:
G.Saxty,
S.J.Woodhead,
V.Berdini,
T.G.Davies,
M.L.Verdonk,
P.G.Wyatt,
R.G.Boyle,
D.Barford,
R.Downham,
M.D.Garrett,
R.A.Carr.
Identification of Inhibitors of Protein Kinase B Using Fragment-Based Lead Discovery. J.Med.Chem. V. 50 2293 2007.
Page generated: Sat Dec 12 09:19:13 2020
ISSN: ISSN 0022-2623 PubMed: 17451234 DOI: 10.1021/JM070091B |
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