Chlorine in PDB 2vof: Structure of Mouse A1 Bound to the Puma BH3-Domain

The structure of Structure of Mouse A1 Bound to the Puma BH3-Domain, PDB code: 2vof was solved by C.Smits, P.E.Czabotar, M.G.Hinds, C.L.Day, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.98 / 1.8
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	49.640, 60.683, 59.986, 90.00, 109.53, 90.00
R / Rfree (%)	18.3 / 21

The binding sites of Chlorine atom in the Structure of Mouse A1 Bound to the Puma BH3-Domain (pdb code 2vof). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of Mouse A1 Bound to the Puma BH3-Domain, PDB code: 2vof:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of Mouse A1 Bound to the Puma BH3-Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of Mouse A1 Bound to the Puma BH3-Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1151 b:20.6 occ:1.00 ND1 A:HIS10 3.0 28.7 1.0 O A:HOH2009 3.1 22.6 1.0 CB A:HIS10 3.7 26.3 1.0 CG A:MSE7 3.7 24.7 1.0 CG A:HIS10 3.8 27.1 1.0 CA A:MSE7 3.9 25.0 1.0 CB A:MSE7 4.1 24.9 1.0 CE1 A:HIS10 4.1 28.1 1.0 O A:MSE7 4.4 24.5 1.0 C A:MSE7 4.7 25.3 1.0 SE A:MSE7 4.8 30.2 1.0 N A:MSE7 4.8 24.2 1.0 O A:LEU6 5.0 24.3 1.0

Chlorine binding site 2 out of 2 in the Structure of Mouse A1 Bound to the Puma BH3-Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of Mouse A1 Bound to the Puma BH3-Domain within 5.0Å range: probe atom residue distance (Å) B Occ C:Cl1150 b:35.6 occ:1.00 O C:HOH2076 2.8 35.5 1.0 OD1 D:ASN149 3.3 35.2 1.0 N C:TRP86 3.3 25.0 1.0 CB C:ASN85 3.4 24.4 1.0 CD1 C:TRP86 3.6 26.8 1.0 ND2 D:ASN149 3.6 30.0 1.0 CA C:ASN85 3.7 25.3 1.0 CG D:ASN149 3.9 31.1 1.0 CH2 C:TRP133 4.0 27.8 1.0 C C:ASN85 4.0 24.8 1.0 CZ2 C:TRP133 4.1 28.0 1.0 CG C:TRP86 4.2 25.6 1.0 CE C:LYS147 4.2 31.6 1.0 CB C:TRP86 4.2 25.9 1.0 CA C:TRP86 4.4 25.2 1.0 NZ C:LYS147 4.4 30.0 1.0 NE1 C:TRP86 4.6 26.1 1.0 CG C:ASN85 4.6 24.4 1.0 CD C:LYS147 4.8 31.7 1.0

C.Smits, P.E.Czabotar, M.G.Hinds, C.L.Day. Structural Plasticity Underpins Promiscuous Binding of the Prosurvival Protein A1. Structure V. 16 818 2008.
ISSN: ISSN 0969-2126
PubMed: 18462686
DOI: 10.1016/J.STR.2008.02.009