Atomistry » Chlorine » PDB 2vo5-2vv7 » 2vr2
Atomistry »
  Chlorine »
    PDB 2vo5-2vv7 »
      2vr2 »

Chlorine in PDB 2vr2: Human Dihydropyrimidinase

Enzymatic activity of Human Dihydropyrimidinase

All present enzymatic activity of Human Dihydropyrimidinase:
3.5.2.2;

Protein crystallography data

The structure of Human Dihydropyrimidinase, PDB code: 2vr2 was solved by M.Welin, T.Karlberg, J.Andersson, C.H.Arrowsmith, H.Berglund, R.D.Busam, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, M.D.Herman, I.Johansson, A.Kallas, T.Kotenyova, L.Lehtio, M.Moche, M.E.Nilsson, T.Nyman, C.Persson, J.Sagemark, L.Svensson, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Wikstrom, P.Nordlund, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.95 / 2.80
Space group P 64 2 2
Cell size a, b, c (Å), α, β, γ (°) 89.650, 89.650, 219.100, 90.00, 90.00, 120.00
R / Rfree (%) 20 / 25.1

Other elements in 2vr2:

The structure of Human Dihydropyrimidinase also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Human Dihydropyrimidinase (pdb code 2vr2). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Dihydropyrimidinase, PDB code: 2vr2:

Chlorine binding site 1 out of 1 in 2vr2

Go back to Chlorine Binding Sites List in 2vr2
Chlorine binding site 1 out of 1 in the Human Dihydropyrimidinase


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Dihydropyrimidinase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1496

b:86.2
occ:1.00
NZ A:LYS88 3.1 60.1 1.0
CE1 A:PHE453 3.7 60.6 1.0
NE2 A:GLN85 3.9 60.1 1.0
CE A:LYS88 4.0 60.6 1.0
CD2 A:HIS420 4.1 56.1 1.0
CD1 A:PHE453 4.3 60.7 1.0
CZ A:PHE453 4.6 60.7 1.0
CB A:HIS420 4.7 56.2 1.0
CG A:HIS420 4.7 56.0 1.0
CD A:GLN85 4.8 60.2 1.0
OE1 A:GLN85 4.9 60.3 1.0
O A:HIS420 4.9 56.4 1.0
CA A:HIS420 5.0 56.3 1.0

Reference:

M.Welin, T.Karlberg, J.Andersson, C.H.Arrowsmith, H.Berglund, R.D.Busam, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, M.D.Herman, I.Johansson, A.Kallas, T.Kotenyova, L.Lehtio, M.Moche, M.E.Nilsson, T.Nyman, C.Persson, J.Sagemark, L.Svensson, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Wikstrom, P.Nordlund. The Crystal Structure of Human Dihydropyrimidinase To Be Published.
Page generated: Sat Dec 12 09:21:24 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy