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Atomistry » Chlorine » PDB 2vv8-2w20 » 2vx0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2vv8-2w20 » 2vx0 » |
Chlorine in PDB 2vx0: EPHB4 Kinase Domain Inhibitor ComplexEnzymatic activity of EPHB4 Kinase Domain Inhibitor Complex
All present enzymatic activity of EPHB4 Kinase Domain Inhibitor Complex:
2.7.10.1; Protein crystallography data
The structure of EPHB4 Kinase Domain Inhibitor Complex, PDB code: 2vx0
was solved by
J.Read,
C.A.Brassington,
I.Green,
E.J.Mccall,
A.L.Valentine,
D.Barratt,
A.G.Leach,
J.G.Kettle,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2vx0:
The structure of EPHB4 Kinase Domain Inhibitor Complex also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the EPHB4 Kinase Domain Inhibitor Complex
(pdb code 2vx0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the EPHB4 Kinase Domain Inhibitor Complex, PDB code: 2vx0: Chlorine binding site 1 out of 1 in 2vx0Go back to Chlorine Binding Sites List in 2vx0
Chlorine binding site 1 out
of 1 in the EPHB4 Kinase Domain Inhibitor Complex
Mono view Stereo pair view
Reference:
C.Bardelle,
D.Cross,
S.Davenport,
J.G.Kettle,
E.J.Ko,
A.G.Leach,
A.Mortlock,
J.Read,
N.J.Roberts,
P.Robins,
E.J.Williams.
Inhibitors of the Tyrosine Kinase EPHB4. Part 1: Structure-Based Design and Optimization of A Series of 2,4-Bis-Anilinopyrimidines. Bioorg.Med.Chem.Lett. V. 18 2776 2008.
Page generated: Sat Dec 12 09:21:55 2020
ISSN: ISSN 0960-894X PubMed: 18434142 DOI: 10.1016/J.BMCL.2008.04.015 |
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