Chlorine in PDB 2waf: Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6)

The structure of Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6), PDB code: 2waf was solved by C.Contreras-Martel, C.Dahout-Gonzalez, A.Dos-Santos-Martins, M.Kotnik, A.Dessen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.25 / 3.29
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	193.897, 51.593, 121.440, 90.00, 112.38, 90.00
R / Rfree (%)	23.7 / 28.7

The binding sites of Chlorine atom in the Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6) (pdb code 2waf). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6), PDB code: 2waf:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl700 b:61.3 occ:1.00 CB A:THR658 3.1 96.1 1.0 O A:ASN656 3.1 93.0 1.0 OG1 A:THR658 3.4 96.9 1.0 CA A:THR658 3.9 95.7 1.0 N A:THR658 4.0 95.5 1.0 CG2 A:THR658 4.0 95.0 1.0 C A:ASN656 4.3 92.0 1.0 C A:LEU657 4.6 93.9 1.0 CB A:LEU657 4.7 91.7 1.0 CD2 A:LEU657 4.8 93.2 1.0 CG A:LEU657 4.8 92.5 1.0

Chlorine binding site 2 out of 2 in the Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Penicillin-Binding Protein 2B (Pbp-2B) From Streptococcus Pneumoniae (Strain R6) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl701 b:63.7 occ:1.00 NH2 A:ARG667 3.4 95.7 1.0 NH1 A:ARG667 3.7 94.7 1.0 OG A:SER664 3.9 86.2 1.0 CZ A:ARG667 4.0 91.3 1.0 ND2 A:ASN606 4.4 95.8 1.0 CB A:SER664 4.5 81.1 1.0 OH A:TYR327 4.9 71.9 1.0

C.Contreras-Martel, C.Dahout-Gonzalez, A.Dos-Santos-Martins, M.Kotnik, A.Dessen. Pbp Active Site Flexibility As the Key Mechanism For Beta-Lactam Resistance in Pneumococci J.Mol.Biol. V. 387 899 2009.
ISSN: ISSN 0022-2836
PubMed: 19233207
DOI: 10.1016/J.JMB.2009.02.024