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Atomistry » Chlorine » PDB 2wps-2wzc » 2wu7 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2wps-2wzc » 2wu7 » |
Chlorine in PDB 2wu7: Crystal Structure of the Human CLK3 in Complex with V25Enzymatic activity of Crystal Structure of the Human CLK3 in Complex with V25
All present enzymatic activity of Crystal Structure of the Human CLK3 in Complex with V25:
2.7.12.1; Protein crystallography data
The structure of Crystal Structure of the Human CLK3 in Complex with V25, PDB code: 2wu7
was solved by
J.R.C.Muniz,
O.Fedorov,
O.King,
P.Filippakopoulos,
A.N.Bullock,
C.Phillips,
T.Heightman,
E.Ugochukwu,
F.Von Delft,
C.H.Arrowsmith,
F.Bracher,
K.Huber,
A.M.Edwards,
J.Weigelt,
C.Bountra,
S.Knapp,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the Human CLK3 in Complex with V25
(pdb code 2wu7). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of the Human CLK3 in Complex with V25, PDB code: 2wu7: Jump to Chlorine binding site number: 1; 2; 3; 4; Chlorine binding site 1 out of 4 in 2wu7Go back to![]() ![]()
Chlorine binding site 1 out
of 4 in the Crystal Structure of the Human CLK3 in Complex with V25
![]() Mono view ![]() Stereo pair view
Chlorine binding site 2 out of 4 in 2wu7Go back to![]() ![]()
Chlorine binding site 2 out
of 4 in the Crystal Structure of the Human CLK3 in Complex with V25
![]() Mono view ![]() Stereo pair view
Chlorine binding site 3 out of 4 in 2wu7Go back to![]() ![]()
Chlorine binding site 3 out
of 4 in the Crystal Structure of the Human CLK3 in Complex with V25
![]() Mono view ![]() Stereo pair view
Chlorine binding site 4 out of 4 in 2wu7Go back to![]() ![]()
Chlorine binding site 4 out
of 4 in the Crystal Structure of the Human CLK3 in Complex with V25
![]() Mono view ![]() Stereo pair view
Reference:
O.Fedorov,
K.Huber,
A.Eisenreich,
P.Filippakopoulos,
O.King,
A.N.Bullock,
D.Szklarczyk,
L.J.Jensen,
D.Fabbro,
J.Trappe,
U.Rauch,
F.Bracher,
S.Knapp.
Specific Clk Inhibitors From A Novel Chemotype For Regulation of Alternative Splicing. Chem.Biol V. 18 67 2011.
Page generated: Fri Jul 11 01:41:26 2025
ISSN: ISSN 1074-5521 PubMed: 21276940 DOI: 10.1016/J.CHEMBIOL.2010.11.009 |
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