|
Atomistry » Chlorine » PDB 2xep-2xmb » 2xhr | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2xep-2xmb » 2xhr » |
Chlorine in PDB 2xhr: Structure of HSP90 with Small Molecule Inhibitor BoundProtein crystallography data
The structure of Structure of HSP90 with Small Molecule Inhibitor Bound, PDB code: 2xhr
was solved by
C.W.Murray,
M.G.Carr,
O.Callaghan,
G.Chessari,
M.Congreve,
S.Cowan,
J.E.Coyle,
R.Downham,
E.Figueroa,
M.Frederickson,
B.Graham,
R.Mcmenamin,
M.A.Obrien,
S.Patel,
T.R.Phillips,
G.Williams,
A.J.Woodhead,
A.J.A.Woolford,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of HSP90 with Small Molecule Inhibitor Bound
(pdb code 2xhr). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Structure of HSP90 with Small Molecule Inhibitor Bound, PDB code: 2xhr: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 2xhrGo back to Chlorine Binding Sites List in 2xhr
Chlorine binding site 1 out
of 3 in the Structure of HSP90 with Small Molecule Inhibitor Bound
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 2xhrGo back to Chlorine Binding Sites List in 2xhr
Chlorine binding site 2 out
of 3 in the Structure of HSP90 with Small Molecule Inhibitor Bound
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 2xhrGo back to Chlorine Binding Sites List in 2xhr
Chlorine binding site 3 out
of 3 in the Structure of HSP90 with Small Molecule Inhibitor Bound
Mono view Stereo pair view
Reference:
C.W.Murray,
M.G.Carr,
O.Callaghan,
G.Chessari,
M.Congreve,
S.Cowan,
J.E.Coyle,
R.Downham,
E.Figueroa,
M.Frederickson,
B.Graham,
R.Mcmenamin,
M.A.O'brien,
S.Patel,
T.R.Phillips,
G.Williams,
A.J.Woodhead,
A.J.A.Woolford.
Fragment-Based Drug Discovery Applied to HSP90. Discovery of Two Lead Series with High Ligand Efficiency. J.Med.Chem. V. 53 5942 2010.
Page generated: Sat Dec 12 09:25:53 2020
ISSN: ISSN 0022-2623 PubMed: 20718493 DOI: 10.1021/JM100059D |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |