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Atomistry » Chlorine » PDB 2xmc-2xs4 » 2xmg | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 2xmc-2xs4 » 2xmg » |
Chlorine in PDB 2xmg: G117H Mutant of Human Butyrylcholinesterase in Complex with VxEnzymatic activity of G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
All present enzymatic activity of G117H Mutant of Human Butyrylcholinesterase in Complex with Vx:
3.1.1.8; Protein crystallography data
The structure of G117H Mutant of Human Butyrylcholinesterase in Complex with Vx, PDB code: 2xmg
was solved by
F.Nachon,
E.Carletti,
M.Wandhammer,
Y.Nicolet,
L.M.Schopfer,
P.Masson,
O.Lockridge,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
(pdb code 2xmg). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the G117H Mutant of Human Butyrylcholinesterase in Complex with Vx, PDB code: 2xmg: Jump to Chlorine binding site number: 1; 2; 3; 4; 5; Chlorine binding site 1 out of 5 in 2xmgGo back to Chlorine Binding Sites List in 2xmg
Chlorine binding site 1 out
of 5 in the G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
Mono view Stereo pair view
Chlorine binding site 2 out of 5 in 2xmgGo back to Chlorine Binding Sites List in 2xmg
Chlorine binding site 2 out
of 5 in the G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
Mono view Stereo pair view
Chlorine binding site 3 out of 5 in 2xmgGo back to Chlorine Binding Sites List in 2xmg
Chlorine binding site 3 out
of 5 in the G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
Mono view Stereo pair view
Chlorine binding site 4 out of 5 in 2xmgGo back to Chlorine Binding Sites List in 2xmg
Chlorine binding site 4 out
of 5 in the G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
Mono view Stereo pair view
Chlorine binding site 5 out of 5 in 2xmgGo back to Chlorine Binding Sites List in 2xmg
Chlorine binding site 5 out
of 5 in the G117H Mutant of Human Butyrylcholinesterase in Complex with Vx
Mono view Stereo pair view
Reference:
F.Nachon,
E.Carletti,
M.Wandhammer,
Y.Nicolet,
L.M.Schopfer,
P.Masson,
O.Lockridge.
X-Ray Crystallographic Snapshots of Reaction Intermediates in the G117H Mutant of Human Butyrylcholinesterase, A Nerve Agent Target Engineered Into A Catalytic Bioscavenge Biochem.J. V. 434 73 2011.
Page generated: Sat Dec 12 09:26:20 2020
ISSN: ISSN 0264-6021 PubMed: 21091433 DOI: 10.1042/BJ20101648 |
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