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Chlorine in PDB 2xpc: Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
Enzymatic activity of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
All present enzymatic activity of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid:
6.3.2.9;
6.3.2.9;
Protein crystallography data
The structure of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid, PDB code: 2xpc
was solved by
I.Sosic,
H.Barreteau,
M.Simcic,
R.Sink,
J.Cesar,
S.Golic-Grdadolnik,
C.Contreras-Martel,
A.Dessen,
A.Amoroso,
B.Joris,
D.Blanot,
S.Gobec,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 46.43 / 1.49 |
| Space group | P 41 |
| Cell size a, b, c (Å), α, β, γ (°) | 65.659, 65.659, 135.642, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 17.4 / 19.9 |
Other elements in 2xpc:
The structure of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid also contains other interesting chemical elements:
| Fluorine | (F) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
(pdb code 2xpc). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid, PDB code: 2xpc:
In total only one binding site of Chlorine was determined in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid, PDB code: 2xpc:
Chlorine binding site 1 out of 1 in 2xpc
Go back to
Chlorine Binding Sites List in 2xpc
Chlorine binding site 1 out
of 1 in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid within 5.0Å range:
|
Reference:
I.Sosi,
H.Barreteau,
M.Sim,
R.Sink,
J.Cesar,
A.Zega,
S.G.Grdadolnik,
C.Contreras-Martel,
A.Dessen,
A.Amoroso,
B.Joris,
D.Blanot,
S.Gobec.
Second-Generation Sulfonamide Inhibitors of D- Glutamic Acid-Adding Enzyme: Activity Optimisation with Conformationally Rigid Analogues of D- Glutamic Acid. Eur.J.Med.Chem V. 46 2880 2011.
ISSN: ISSN 0223-5234
PubMed: 21524830
DOI: 10.1016/J.EJMECH.2011.04.011
Page generated: Sat Jul 20 14:05:18 2024
ISSN: ISSN 0223-5234
PubMed: 21524830
DOI: 10.1016/J.EJMECH.2011.04.011
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