Chlorine »
PDB 2xmd-2xs6 »
2xpc »
Chlorine in PDB 2xpc: Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
Enzymatic activity of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
All present enzymatic activity of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid:
6.3.2.9;
6.3.2.9;
Protein crystallography data
The structure of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid, PDB code: 2xpc
was solved by
I.Sosic,
H.Barreteau,
M.Simcic,
R.Sink,
J.Cesar,
S.Golic-Grdadolnik,
C.Contreras-Martel,
A.Dessen,
A.Amoroso,
B.Joris,
D.Blanot,
S.Gobec,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 46.43 / 1.49 |
| Space group | P 41 |
| Cell size a, b, c (Å), α, β, γ (°) | 65.659, 65.659, 135.642, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 17.4 / 19.9 |
Other elements in 2xpc:
The structure of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid also contains other interesting chemical elements:
| Fluorine | (F) | 1 atom |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
(pdb code 2xpc). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid, PDB code: 2xpc:
In total only one binding site of Chlorine was determined in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid, PDB code: 2xpc:
Chlorine binding site 1 out of 1 in 2xpc
Go back to
Chlorine Binding Sites List in 2xpc
Chlorine binding site 1 out
of 1 in the Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Second-Generation Sulfonamide Inhibitors of Murd: Activity Optimisation with Conformationally Rigid Analogues of D-Glutamic Acid within 5.0Å range:
|
Reference:
I.Sosi,
H.Barreteau,
M.Sim,
R.Sink,
J.Cesar,
A.Zega,
S.G.Grdadolnik,
C.Contreras-Martel,
A.Dessen,
A.Amoroso,
B.Joris,
D.Blanot,
S.Gobec.
Second-Generation Sulfonamide Inhibitors of D- Glutamic Acid-Adding Enzyme: Activity Optimisation with Conformationally Rigid Analogues of D- Glutamic Acid. Eur.J.Med.Chem V. 46 2880 2011.
ISSN: ISSN 0223-5234
PubMed: 21524830
DOI: 10.1016/J.EJMECH.2011.04.011
Page generated: Sat Jul 20 14:05:18 2024
ISSN: ISSN 0223-5234
PubMed: 21524830
DOI: 10.1016/J.EJMECH.2011.04.011
Last articles
Zn in 9J0NZn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
