Chlorine in PDB 2xxt: Crystal Structure of the GLUK2 (GLUR6) Wild-Type Lbd Dimer in Complex with Kainate

The structure of Crystal Structure of the GLUK2 (GLUR6) Wild-Type Lbd Dimer in Complex with Kainate, PDB code: 2xxt was solved by N.Nayeem, O.Mayans, T.Green, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.72 / 1.90
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	97.285, 105.915, 113.478, 90.00, 90.00, 90.00
R / Rfree (%)	17.2 / 21

The structure of Crystal Structure of the GLUK2 (GLUR6) Wild-Type Lbd Dimer in Complex with Kainate also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of the GLUK2 (GLUR6) Wild-Type Lbd Dimer in Complex with Kainate (pdb code 2xxt). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the GLUK2 (GLUR6) Wild-Type Lbd Dimer in Complex with Kainate, PDB code: 2xxt:

Chlorine binding site 1 out of 1 in the Crystal Structure of the GLUK2 (GLUR6) Wild-Type Lbd Dimer in Complex with Kainate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the GLUK2 (GLUR6) Wild-Type Lbd Dimer in Complex with Kainate within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl901 b:53.9 occ:0.70 O A:HOH2191 2.9 54.1 1.0 NZ B:LYS531 3.1 22.6 1.0 NZ A:LYS531 3.7 26.2 1.0 CG B:LYS531 4.0 26.7 1.0 O B:PHE529 4.0 19.7 1.0 NH1 A:ARG775 4.1 72.3 1.0 CE B:LYS531 4.1 23.6 1.0 O A:HOH2092 4.1 37.9 1.0 OG1 B:THR779 4.1 15.8 1.0 O A:PHE529 4.2 21.1 1.0 NH1 B:ARG775 4.3 74.5 1.0 N B:LYS531 4.4 19.9 1.0 CD B:ARG775 4.4 54.8 1.0 CE A:LYS531 4.7 23.1 1.0 CD B:LYS531 4.7 29.4 1.0 C B:SER530 4.7 24.1 1.0 CD A:LYS531 4.8 30.2 1.0 CD A:ARG775 4.8 54.4 1.0 O B:HOH2077 4.9 35.6 1.0 CA B:LYS531 4.9 17.4 1.0 CZ A:ARG775 4.9 69.6 1.0

N.Nayeem, O.Mayans, T.Green. Conformational Flexibility of the Ligand-Binding Domain Dimer in Kainate Receptor Gating and Desensitization J.Neurosci. V. 31 2916 2011.
ISSN: ISSN 0270-6474
PubMed: 21414913
DOI: 10.1523/JNEUROSCI.4771-10.2011