Chlorine in PDB 2xzc: Crystal Structure of Phosphonate-Modified Recombinant A.17 Antibody Fab Fragment

The structure of Crystal Structure of Phosphonate-Modified Recombinant A.17 Antibody Fab Fragment, PDB code: 2xzc was solved by E.Carletti, F.Nachon, Y.Nicolet, P.Masson, I.Kurkova, I.Smirnov, A.Friboulet, A.Tramontano, A.Gabibov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.32 / 1.36
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	52.560, 66.950, 66.210, 90.00, 107.65, 90.00
R / Rfree (%)	16.172 / 19.137

The binding sites of Chlorine atom in the Crystal Structure of Phosphonate-Modified Recombinant A.17 Antibody Fab Fragment (pdb code 2xzc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Phosphonate-Modified Recombinant A.17 Antibody Fab Fragment, PDB code: 2xzc:

Chlorine binding site 1 out of 1 in the Crystal Structure of Phosphonate-Modified Recombinant A.17 Antibody Fab Fragment


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Phosphonate-Modified Recombinant A.17 Antibody Fab Fragment within 5.0Å range: probe atom residue distance (Å) B Occ H:Cl1221 b:11.6 occ:0.80 O L:HOH2084 3.1 16.3 1.0 N H:ALA107 3.2 11.0 1.0 O H:HOH2265 3.2 23.0 1.0 NE1 H:TRP109 3.4 16.5 1.0 CB L:LEU47 3.8 9.0 1.0 CE2 L:TYR37 3.8 8.5 1.0 CB H:ALA107 3.9 13.1 1.0 C7 L:XOP1217 3.9 14.7 1.0 CA H:ASP106 3.9 15.3 1.0 O H:ALA107 4.0 12.4 1.0 CA H:ALA107 4.0 12.5 1.0 C H:ASP106 4.0 13.4 1.0 C13 L:XOP1217 4.0 15.8 1.0 CD1 H:TRP109 4.2 19.7 1.0 O1 L:XOP1217 4.2 14.2 1.0 CD2 L:LEU47 4.3 11.2 1.0 CE2 H:TRP109 4.4 17.1 1.0 C H:ALA107 4.4 11.6 1.0 CG L:LEU47 4.5 7.7 1.0 N L:LEU47 4.5 7.8 1.0 CB H:ASP106 4.5 17.8 1.0 CD1 L:LEU47 4.6 9.9 1.0 O H:ASN105 4.6 18.6 1.0 CA L:LEU47 4.6 7.1 1.0 OD2 H:ASP106 4.6 25.5 1.0 CD2 L:TYR37 4.6 8.1 1.0 CZ L:TYR37 4.7 7.9 1.0 OH L:TYR37 4.7 11.5 1.0 CZ2 H:TRP109 4.7 17.4 1.0 P L:XOP1217 4.8 11.7 1.0 C8 L:XOP1217 4.8 14.2 1.0 O2 L:XOP1217 4.8 14.1 1.0 CG H:ASP106 5.0 25.6 1.0

I.Smirnov, E.Carletti, I.Kurkova, F.Nachon, Y.Nicolet, V.A.Mitkevich, H.Debat, B.Avalle, A.A.Belogurov, N.Kuznetsov, A.Reshetnyak, P.Masson, A.G.Tonevitsky, N.Ponomarenko, A.A.Makarov, A.Friboulet, A.Tramontano, A.Gabibov. Reactibodies Generated By Kinetic Selection Couple Chemical Reactivity with Favorable Protein Dynamics. Proc.Natl.Acad.Sci.Usa V. 108 15954 2011.
ISSN: ISSN 0027-8424
PubMed: 21896761
DOI: 10.1073/PNAS.1108460108