Chlorine in PDB 2y4r: Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa

All present enzymatic activity of Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa:
4.1.3.38;

The structure of Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa, PDB code: 2y4r was solved by P.E.F.O'rourke, T.C.Eadsforth, P.K.Fyfe, S.M.Shepard, M.Agacan, W.N.Hunter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	101.34 / 1.75
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	40.813, 66.817, 202.688, 90.00, 90.00, 90.00
R / Rfree (%)	16.7 / 21.5

The binding sites of Chlorine atom in the Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa (pdb code 2y4r). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa, PDB code: 2y4r:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1275 b:55.1 occ:1.00 NH2 A:ARG102 3.5 18.0 1.0 NH1 A:ARG102 3.6 20.0 1.0 CZ A:ARG102 4.1 19.9 1.0 CB A:ASP6 4.4 17.9 1.0 O A:ASP6 4.5 20.1 1.0 CG A:ASP6 4.8 22.7 1.0 O A:HOH2005 4.8 27.8 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1276 b:65.2 occ:1.00 NE A:ARG122 3.2 19.7 1.0 NH2 A:ARG122 3.5 19.5 1.0 CZ A:ARG122 3.8 17.7 1.0 CD A:ARG122 4.2 19.8 1.0 CB A:ARG122 4.9 12.9 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of 4-Amino-4-Deoxychorismate Lyase From Pseudomonas Aeruginosa within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1282 b:57.5 occ:1.00 NE2 A:HIS168 3.5 21.4 1.0 NE2 B:HIS168 3.6 21.4 1.0 O A:HOH2040 4.0 34.1 1.0 CD2 A:HIS168 4.3 21.5 1.0 CE1 A:HIS168 4.5 20.2 1.0 CD2 B:HIS168 4.5 21.1 1.0 CE1 B:HIS168 4.6 22.9 1.0

P.E.F.O'rourke, T.C.Eadsforth, P.K.Fyfe, S.M.Shepherd, W.N.Hunter. Pseudomonas Aeruginosa 4-Amino-4-Deoxychorismate Lyase: Spatial Conservation of An Active Site Tyrosine and Classification of Two Types of Enzyme. Plos One V. 6 24158 2011.
ISSN: ESSN 1932-6203
PubMed: 21935381
DOI: 10.1371/JOURNAL.PONE.0024158